merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1379,Anti-CD54 Antibody, extracellular, clone 84H10

  • merck millipore,默克密理博,MAB1379,Anti-CD54 Antibody, extracellular, clone 84H10

    产品名称：Anti-CD54 Antibody, extracellular, clone 84H10
    产品型号：MAB1379
    Detect CD54 using this Anti-CD54 Antibody, extracellular, clone 84H10 validated for use in FC, IP, IH.

    merck millipore,默克密理博,MAB1379,Anti-CD54 Antibody, extracellular, clone 84H10

  • 产品介绍
  • merck millipore,默克密理博,MAB1379,Anti-CD54 Antibody, extracellular, clone 84H10

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1379
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-CD54 Antibody, extracellular, clone 84H10
    Alternate Names
    • ICAM-1
    背景信息 This molecule is inducible to high levels by mitogenic lectins on lymphocytes and by IL-1beta or IFN gamma on other cell types such as fibroblasts and enthothelial cells.
    产品信息
    格式 Purified
    演示 Affinity purified immunoglobulin. Liquid in Phosphate buffered saline, pH 7.4, containing 0.09% sodium azide.
    应用
    应用 Detect CD54 using this Anti-CD54 Antibody, extracellular, clone 84H10 validated for use in FC, IP, IH.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    不建议的应用
    • Immunohistochemistry (Paraffin)
    应用说明 Flow Cytometry: Neat - 1:10. 10 μL of suggested dilution will label 10e6 cells.

    Immunohistochemistry on frozen tissue sections: 1:20-1:50. Does not work on paraffin embedded tissue sections.

    Immunoprecipitation: 5 μg/ 10e7 cells

    Adhesion Blocking; blocks ICAM-1 mediated adhesion to LFA-1.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 K562 cell line
    表位 extracellular
    克隆 84H10
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes the extracellular D1 domain of ICAM-1. Blocks binding of LFA-1 and P. falciparum to ICAM-1. Reacts with the ICAM-1 antigen found in low levels on lymphocytes and strongly expressed on monocytes and granulocytes. Detects an antigen of 90 kDa.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000201.1
    Entrez基因汇总 ICAM1 (CD54) is typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. ICAM1 is also exploited by Rhinovirus as a receptor.
    基因符号
    • ICAM-1
    • ICAM1
    • P3.58
    • BB2
    • CD54
    非反应性品种
    • Canine
    UniProt编号
    • P05362
    UniProt汇总 FUNCTION: SwissProt: P05362 # ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). In case of rhinovirus infection acts as a cellular receptor for the virus. Also acts as receptor for some coxsackieviruses.
    SIZE: 532 amino acids; 57825 Da
    SUBUNIT: Interacts with human herpesvirus 8 MIR2 protein (Probable).
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    PTM: Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
    SIMILARITY: SwissProt: P05362 ## Belongs to the immunoglobulin superfamily. ICAM family. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2-8°C for up to 12 months from date of receipt. Alternatively, this antibody can be stored at -20ºC. Avoid repeated freeze-thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB1379,Anti-CD54 Antibody, extracellular, clone 84H10

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下一件merck millipore产品：merck millipore,默克密理博,12-457,MYPT1 (654-880)


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