merck millipore,默克密理愽
  • merck millipore,默克密理博,IL020,Interleukin-10 Protein, Recombinant mouse

  • merck millipore,默克密理博,IL020,Interleukin-10 Protein, Recombinant mouse

    产品名称：Interleukin-10 Protein, Recombinant mouse
    产品型号：IL020
    The recombinant mouse Interleukin-10 protein, originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology w More>>

    merck millipore,默克密理博,IL020,Interleukin-10 Protein, Recombinant mouse

  • 产品介绍
  • merck millipore,默克密理博,IL020,Interleukin-10 Protein, Recombinant mouse

    重要规格表

    主要应用 品种 纯度
    CULTMouseGreater than 98% by SDS-PAGE.
    描述
    产品目录编号 IL020
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Interleukin-10 Protein, Recombinant mouse
    概述 Interleukin-10 (IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. The reported biological activities of IL-10, which may be inter-related, include inhibition of macrophage mediated cytokine synthesis, suppression of the delayed-type hypersensitivity response, and stimulation of the Th2 cell response which results in elevated antibody production.
    Alternate Names
    • IL-10
    产品信息
    演示 Lyophilized from 3mM Tris, pH 8.0 with no additives.
    应用
    应用 The recombinant mouse Interleukin-10 protein, originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI.
    主要应用
    • Cell Culture
    应用说明 For most in vitro applications, IL-10 exerts its biological activity in the concentration range of 0.2 to 20.0 ng/mL. Responding cells are (partial list): T-cells, macrophages.
    生物信息
    纯度 Greater than 98% by SDS-PAGE.
    品种 Mouse
    特异活性 Chemicon's mouse IL-10 is fully biologically active as measured by the dose dependent co-stimulation (with IL-4) of MC-9 cells. The ED(50) was found to be <=2 ng/mL, corresponding to a specific activity of 5 x 10(E5) units/mg.
    Entrez基因汇总 The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
    UniProt编号
    • P18893
    • P15248
    UniProt汇总 FUNCTION: SwissProt: P15248 # Supports IL-2 independent and IL-4 independent growth of helper T-cells.
    SIZE: 144 amino acids; 15909 Da
    SUBCELLULAR LOCATION: Secreted.
    SIMILARITY: SwissProt: P15248 ## Belongs to the IL-7/IL-9 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute in water to a concentration of 1 mg/ml. This solution can be diluted into other buffered solutions or stored at -20°C for future use.
    包装信息
    数量 10 µg

    merck millipore,默克密理博,IL020,Interleukin-10 Protein, Recombinant mouse

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