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  • merck millipore,默克密理博,IL010,Interleukin-10 Protein, Recombinant human

  • merck millipore,默克密理博,IL010,Interleukin-10 Protein, Recombinant human

    产品名称：Interleukin-10 Protein, Recombinant human
    产品型号：IL010
    The recombinant human Interleukin-10 protein originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology wi More>>

    merck millipore,默克密理博,IL010,Interleukin-10 Protein, Recombinant human

  • 产品介绍
  • merck millipore,默克密理博,IL010,Interleukin-10 Protein, Recombinant human

    重要规格表

    主要应用 品种 纯度
    CULTHumanGreater than 98% by SDS-PAGE and FPLC analysi
    描述
    产品目录编号 IL010
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Interleukin-10 Protein, Recombinant human
    概述 Interleukin-10 (IL-10) originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.6 kDa protein that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. The reported biological activities of IL-10, which may be interrelated, include inhibition of macrophage mediated cytokine synthesis, suppression of the delayed-type hyper-sensitivity response, and stimulation of the Th2 cell response which results in elevated antibody production.
    Alternate Names
    • IL-10
    产品信息
    演示 Lyophilized from 5 mM Tris, pH 8.2.
    应用
    应用 The recombinant human Interleukin-10 protein originally known as Cytokine Synthesis Inhibitory Factor (CSIF) is an 18.7 kDa protein of 160 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI.
    主要应用
    • Cell Culture
    应用说明 For most in vitro applications, IL-10 exerts its biological activity in the concentration range of 0.2 to 20.0 ng/mL.
    生物信息
    纯度 Greater than 98% by SDS-PAGE and FPLC analysi
    品种 Human
    特异活性 Human IL-10 is fully biologically active as measured by the dose dependent co-stimulation (with mouse IL-4) of MC/9 cells. The ED(50) was found to be <= 2 ng/mL, corresponding to a specific activity of >= 5 x 10(E5) units/mg.
    Entrez基因编号
    • NM_000590.1
    Entrez基因汇总 The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
    基因符号
    • HP40
    • IL9
    • P40
    • IL-9
    UniProt编号
    • P15248
    UniProt汇总 FUNCTION: SwissProt: P15248 # Supports IL-2 independent and IL-4 independent growth of helper T-cells.
    SIZE: 144 amino acids; 15909 Da
    SUBCELLULAR LOCATION: Secreted.
    SIMILARITY: SwissProt: P15248 ## Belongs to the IL-7/IL-9 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute in 5 mM Tris, pH 8.2 to a concentration 1 mg/mL. This solution can be diluted into other aqueous buffers. Reconstituted IL-10dap kinase mouse

    should be stored in undiluted aliquots at -20°C for up to six months.
    包装信息
    数量 10 µg

    merck millipore,默克密理博,IL010,Interleukin-10 Protein, Recombinant human

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