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  • merck millipore,默克密理博,IL008,Interleukin-8 Protein, Recombinant human, (72 amino acid form)

  • merck millipore,默克密理博,IL008,Interleukin-8 Protein, Recombinant human, (72 amino acid form)

    产品名称：Interleukin-8 Protein, Recombinant human, (72 amino acid form)
    产品型号：IL008
    The recombinant Human interleukin-8 protein (or IL-8 protein) is an 8.4 kDa protein containing 72 amino acid residues.

    merck millipore,默克密理博,IL008,Interleukin-8 Protein, Recombinant human, (72 amino acid form)

  • 产品介绍
  • merck millipore,默克密理博,IL008,Interleukin-8 Protein, Recombinant human, (72 amino acid form)

    重要规格表

    主要应用 品种 纯度
    CULTHumanGreater than 98% by SDS-PAGE and HPLC analysis
    描述
    产品目录编号 IL008
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Interleukin-8 Protein, Recombinant human, (72 amino acid form)
    概述 Human interleukin-8 (IL-8) is an 8.4 kDa protein containing 72 amino acid residues. It promotes neutrophil chemotaxis and degranulation. The 72 amino acid IL-8 is the predominant form secreted by monocytes and lymphocytes.
    Alternate Names
    • IL-8
    产品信息
    演示 Lyophilized powder with no additives.
    应用
    应用 The recombinant Human interleukin-8 protein (or IL-8 protein) is an 8.4 kDa protein containing 72 amino acid residues.
    主要应用
    • Cell Culture
    生物信息
    纯度 Greater than 98% by SDS-PAGE and HPLC analysis
    品种 Human
    特异活性 Human IL-8 produces chemotaxis over a wide concentration range in an assay using human peripheral blood neutrophils. Significant chemotaxis was achieved using a concentration of 10-100 ng/mL.
    Entrez基因编号
    • NM_000584.2
    Entrez基因汇总 The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
    基因符号
    • NAF
    • IL8
    • GCP-1
    • emoctakin
    • MDNCF
    • NAP1
    • CXCL8
    • AMCF-I
    • IL-8
    • Emoctakin
    • TSG-1
    • NAP-1
    • LYNAP
    • MONAP
    • GCP1
    • SCYB8
    • LUCT
    • K60
    • LECT
    • 3-10C
    • b-ENAP
    UniProt编号
    • P10145
    UniProt汇总 FUNCTION: SwissProt: P10145 # IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
    SIZE: 99 amino acids; 11098 Da
    SUBUNIT: Homodimer.
    SUBCELLULAR LOCATION: Secreted.
    PTM: Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.
    SIMILARITY: SwissProt: P10145 ## Belongs to the intercrine alpha (chemokine CxC) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other buffered solutions. Reconstituted IL-8 should be stored in undiluted aliquots at -20°C for up to six months.
    包装信息
    数量 25 µg

    merck millipore,默克密理博,IL008,Interleukin-8 Protein, Recombinant human, (72 amino acid form)

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