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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-280 品牌系列 Upstate
商名 - Upstate
描述 Anti-PEDF Antibody 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Anti-PEDF Antibody is an antibody against PEDF for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 His tagged fusion protein corresponding to full length human PEDF (Pigment Epitheliuml Derived Factor) expressed in baby hamster kidney cells 宿主 Rabbit 特异性 PEDF 同种型 IgG 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_002615
基因符号 - PIG35
- SERPINF1
- EPC-1
- PEDF
- Serpin-F1
纯化方法 Protein A chromatography UniProt编号 - P36955
UniProt汇总 FUNCTION: SwissProt: P36955 # Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
SIZE: 418 amino acids; 46342 Da
SUBCELLULAR LOCATION: Secreted. Melanosome. Note=Enriched in stage I melanosomes.
TISSUE SPECIFICITY: Retinal pigment epithelial cells and blood plasma.
DEVELOPMENTAL STAGE: Expressed in quiescent cells.
DOMAIN: SwissProt: P36955 The N-terminal (AA 44-121) exhibits neurite outgrowth- inducing activity. The C-terminal exposed loop (AA 382-418) is essential for serpin activity.
PTM: The N-terminus is blocked.
SIMILARITY: Belongs to the serpin family.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from Y79 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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