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来源 纯度 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 描述 产品目录编号 GF434 商名 - HumanKine®
描述 HumanKine® Noggin, Human Recombinant Xeno-Free Alternate Names - SYNS1
- SYM1
- NOG
背景信息 Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. 产品信息 配方 演示 Product is presented in PBS and filtered through a 0.2 micron filter before lyophilization. 生物信息 纯度 Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 来源 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. UniProt编号 - Q13253
产品使用声明 质量保证 Bioactivity assay: Determined by the dose dependent inhibition of rhBMP4 induced alkaline phosphate production by ATDC5 cells. ED50 is typically 20-100 ng/ml. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added. 包装信息 数量 10 µg
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