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merck millipore,默克密理博,GF307,β-NGF Protein, Human Recombinant Animal Free
产品名称:β-NGF Protein, Human Recombinant Animal Free
产品型号:GF307
The Nerve Growth Factor is a well characterized neurotropic protein that plays a critical role in the development of sympathetic & some sensory neurons in the peripheral nervous system. Manufactured u More>>
merck millipore,默克密理博,GF307,β-NGF Protein, Human Recombinant Animal Free
- 产品介绍
重要规格表
来源 纯度 E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses 描述 产品目录编号 GF307 描述 β-NGF Protein, Human Recombinant Animal Free Alternate Names - Beta NGF
- Nerve Growth Factor
- NGF
- BNGF
背景信息 Nerve Growth Factor (β-NGF) is a well characterized neurotropic protein that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. In addition, NGF can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. NGF has also been shown to have biological effects on nonneuronal tissues. β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (238 total amino acid residues). The three disulfide bonds are required for biological activity. 产品信息 配方 演示 Product is filtered through a 0.2 micron filter before lyophilization. 应用 应用 The Nerve Growth Factor is a well characterized neurotropic protein that plays a critical role in the development of sympathetic & some sensory neurons in the peripheral nervous system. Manufactured using all non-animal reagents. 生物信息 纯度 Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses 来源 E. coli 交叉反应性 Chicken, Hamster, Mouse, Rat Entrez基因编号 - NM_002506.2
UniProt编号 - P01138
产品使用声明 质量保证 Bioactivity assay: Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.储存和货运信息 存储条件 Store at -20°C for up to 6 months from date of receipt. 包装信息 数量 20 µg
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