merck millipore,默克密理博,GF048,Macrophage Inflammatory Protein-1α Protein, Recombinant rat

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Merck Millipore 默克密理愽

主要应用	品种	来源	纯度
CULT	Rat	E. coli	Greater than 95% by SDS-PAGE and HPLC analysis.

描述
产品目录编号	GF048
品牌系列	Chemicon®
商名	Chemicon
描述	Macrophage Inflammatory Protein-1α Protein, Recombinant rat
概述	Rat macrophage inflammatory protein-1alpha (MIP-1alpha) is an 7.8 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue macrophages.
Alternate Names	MIP-1alpha

产品信息
演示	Lyophilized powder with no additives.

应用
应用	The rat macrophage inflammatory protein-1alpha ( or MIP-1alpha protein) is an 7.8 kDa protein containing 69 amino acid residues.
主要应用	Cell Culture

生物信息
纯度	Greater than 95% by SDS-PAGE and HPLC analysis.
来源	E. coli
品种	Rat
特异活性	GF048 produces chemotaxis over a wide concentration range in an assay using rat peritoneal macrophages. Significant chemotaxis was achieved using a concentration of 50-100 ng/mL.
Entrez基因汇总	Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988 [PubMed 3279154]). Sherry et al. (1988) [PubMed 3058856] demonstrated 2 protein components of MIP1, called by them alpha and beta.[supplied by OMIM]
UniProt编号	P50229 P10147
UniProt汇总	FUNCTION: SwissProt: P10147 # Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). SIZE: 92 amino acids; 10085 Da SUBUNIT: Self-associates. Also heterodimer of MIP-1-alpha(4-69) and MIP-1-beta(3-69). SUBCELLULAR LOCATION: Secreted. PTM: N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T- cells. SIMILARITY: SwissProt: P10147 ## Belongs to the intercrine beta (chemokine CC) family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized powder, though stable at room temperature, is best stored at -20°C. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Further dilutions can be made into other aqueous buffers and stored at 2-8 ºC for 1 week or -20 ºC for future use. Reconstituted rat MIP-1alpha should be stored in undiluted aliquots at -20°C for up to 6 months.

包装信息
数量	20 µg

merck millipore,默克密理博,GF048,Macrophage Inflammatory Protein-1α Protein, Recombinant rat

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