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merck millipore,默克密理博,GF021,Stem Cell Factor Protein, Recombinant human
产品名称：Stem Cell Factor Protein, Recombinant human
产品型号：GF021
The Stem Cell Factor (SCF) Protein, Recombinant human, is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis.
merck millipore,默克密理博,GF021,Stem Cell Factor Protein, Recombinant human
- 产品介绍
重要规格表
品种 来源 纯度 Human E.coli Greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of SCF. 描述 产品目录编号 GF021 品牌系列 Chemicon®
商名 - Chemicon
描述 Stem Cell Factor Protein, Recombinant human 概述 Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. Recombinant human SCF is an 18.4 kDa protein containing 165 amino acid residues corresponding to the soluble secreted form of SCF. Alternate Names - c-kit Ligand
- SCF
- Mast Cell Growth Factor
- MGF
产品信息 演示 The sterile filtered solution was lyophilized from 10mM Acetic acid. 应用 应用 The Stem Cell Factor (SCF) Protein, Recombinant human, is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. 应用说明 For most in vitro applications, SCF exerts its biological activity in the concentration range of 0.2 to 20.0 ng/mL. Responding cells are (partial list): Stem cells, BM precursor cells. 生物信息 纯度 Greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of SCF. 来源 E.coli 品种 Human 特异活性 Chemicon's human SCF is fully biologically active when compared to standards. The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <= 2 ng/mL, corresponding to a specific activity of >= 5 x 10e5 units/mg. Entrez基因编号 - NM_003994.4
- NM_000899.3
Entrez基因汇总 This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. 基因符号 - KL-1
- KITLG
- DKFZp686F2250
- SCF
- SF
- MGF
- Kitl
UniProt编号 - P21583
UniProt汇总 FUNCTION: SwissProt: P21583 # Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins.
SIZE: 273 amino acids; 30899 Da
SUBUNIT: Homodimer, non-covalently linked (Probable).
SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein (By similarity). Note=Also exists as a secreted soluble form (isoform 1 only) (By similarity). & Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity).
DEVELOPMENTAL STAGE: Acts in the early stages of hematopoiesis.
PTM: A soluble form is produced by proteolytic processing of isoform 1 in the extracellular domain.
SIMILARITY: SwissProt: P21583 ## Belongs to the SCF family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 The lyophilized powder, though stable for a few weeks at room temperature, is best stored at -20°C. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can be further diluted into other aqueous buffers and stored at 2-8°C for 1 week or -20°C for future use. Reconstituted SCF should be stored in undiluted aliquots at -20°C. Avoid repeated freeze/thaw cycles. 包装信息 数量 10 µg
上一件merck millipore产品：merck millipore,默克密理博,CBL419,Anti-Eosinophil Major Basic Protein Antibody, clone BMK13
下一件merck millipore产品：merck millipore,默克密理博,MAB16200,Anti-MGMT Antibody, clone MT3.1
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