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merck millipore,默克密理博,FCMAB261P,Milli-Mark™ Anti-Eck/EphA2-PE Antibody, clone D7
产品名称：Milli-Mark™ Anti-Eck/EphA2-PE Antibody, clone D7
产品型号：FCMAB261P
Milli-Mark Anti-Eck/EphA2-PE Antibody, clone D7 is an antibody against Eck/EphA2 for use in FC.
merck millipore,默克密理博,FCMAB261P,Milli-Mark™ Anti-Eck/EphA2-PE Antibody, clone D7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 FCMAB261P 商名 - Milli-Mark
描述 Milli-Mark™ Anti-Eck/EphA2-PE Antibody, clone D7 Alternate Names - receptor protein tyrosine kinase regulated by p53 and E2F-1
- EPH receptor A2
- Epithelial cell kinase
- Tyrosine-protein kinase receptor ECK
- ephrin receptor EphA2
- epithelial cell receptor protein tyrosine kinase
- protein tyrosine kinase
背景信息 EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.产品信息 格式 Phycoerythrin 控制 - A431 cells
演示 Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Milli-Mark Anti-Eck/EphA2-PE Antibody, clone D7 is an antibody against Eck/EphA2 for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Native protein isolated by purification of phosphotyrosine-containing proteins. 克隆 clone D7 宿主 Mouse 特异性 Antibody recognizes Epithelial Cell Kinase (Eck/EphA2). 同种型 IgG1 品种反应性 Human Species Reactivity Note Tested and passed on Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_004422
Entrez基因汇总 This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. 基因符号 - ECK
- EPHA2
- EphA2
纯化方法 Protein G Purified UniProt编号 - P29317
UniProt汇总 FUNCTION: SwissProt: P29317 # Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5.
SIZE: 976 amino acids; 108254 Da
SUBUNIT: Interacts with SLA (By similarity). Interacts with INPPL1/SHIP2.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g., skin, intestine, lung, and ovary.
SIMILARITY: SwissProt: P29317 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.产品使用声明 质量保证 Evaluated by flow cytometry using A431 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt. 包装信息 数量 100 tests
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