merck millipore,默克密理博,FCMAB245P,Milli-Mark™ Anti-mouse Interleukin-4-PE Antibody, clone 11B11

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	FC	R	Phycoerythrin	Monoclonal Antibody

描述
产品目录编号	FCMAB245P
商名	Milli-Mark
描述	Milli-Mark™ Anti-mouse Interleukin-4-PE Antibody, clone 11B11
Alternate Names	interleukin 4 B cell growth factor 1 B-cell stimulatory factor 1 B_cell stimulatory factor 1 Lymphocyte stimulatory factor 1
背景信息	Interleukin-4 (IL-4) is a cytokine that stimulates activated B-cell and T-cell proliferation and induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. These Th2 cells, in turn, also produce IL-4. IL-4 also acts as a key regulator in humoral and adaptive immunity and induces B-cell class switching to IgE, as well as up-regulating MHC class II production. Mutations in the IL-4 gene may lead to a susceptibility to ischemic stroke or cerebral infarction. Overproduction of IL-4 is associated with allergies.

产品信息
格式	Phycoerythrin
控制	Mick2 cells
演示	Purified rat monoclonal IgG1κ conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.

应用
应用	Milli-Mark Anti-mouse Interleukin-4-PE Antibody, clone 11B11 detects level of mouse Interleukin-4 & has been published & validated for use in FC.
主要应用	Flow Cytometry

生物信息
免疫原品种	Recombinant protein corresponding to mouse IL-4.
克隆	11B11
宿主	Rat
特异性	Antibody recognizes IL-4.
同种型	IgG1κ
品种反应性	Mouse
Species Reactivity Note	Tested and passed on mouse.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_067258.1
基因符号	IL-4 IL4 Binetrakin Pitrakinra BSF1 BSF-1
纯化方法	Protein G Purified
UniProt编号	P07750
UniProt汇总	FUNCTION: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. SUBCELLULAR LOCATION: Secreted. SEQUENCE SIMILARITIES: Belongs to the IL-4/IL-13 family.

产品使用声明
质量保证	Evaluated by flow cytometry using Mick2 cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB245P,Milli-Mark™ Anti-mouse Interleukin-4-PE Antibody, clone 11B11

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