merck millipore,默克密理博,FCMAB189F,Milli-Mark™ Anti-CD25-FITC Antibody, clone ACT-1

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	FITC	Monoclonal Antibody

描述
产品目录编号	FCMAB189F
商名	Milli-Mark
描述	Milli-Mark™ Anti-CD25-FITC Antibody, clone ACT-1
Alternate Names	TAC antigen Interleukin-2 receptor subunit alpha IL-2 receptor subunit alpha IL-2-RA p55
背景信息	The interleukin-2 receptors consist of three polypeptides (α, β, γ), which in different combinations bind IL-2 (Ishii, 1995). The 55 kDa α-chain is called CD25. CD25 is strongly expressed on the surface of activated T cells (Uchiyama, 1981), and is also expressed on B cells stimulated with anti-IgM antibody, and on monocytes/macrophages stimulated with lipopolysaccharide (Sugamura, 1997). In normal peripheral blood a variable expression on lymphoid cells (about 3-25%) is observed. The specificity of Anti-CD25, ACT-1, is identical to that of CD25-clustered antibodies (Schwarting, 1987; Aziz, 1996).

产品信息
格式	FITC
控制	Human Lymphocytes
演示	Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

应用
应用	This Milli-Mark Anti-CD25-FITC Antibody, clone ACT-1 is validated for use in FC for the detection of CD25.
主要应用	Flow Cytometry

生物信息
免疫原品种	Phytohemagglutinin-stimulated blood lymphocytes
克隆	ACT-1
宿主	Mouse
特异性	Antibody recognizes Human CD25 antigen.
同种型	IgG1κ
品种反应性	Human
Species Reactivity Note	Tested and passed on Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_000408
Entrez基因汇总	The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
纯化方法	Protein A Purified
UniProt编号	P01589

产品使用声明
质量保证	Evaluated by flow cytometry using human lymphocytes
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB189F,Milli-Mark™ Anti-CD25-FITC Antibody, clone ACT-1

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