merck millipore,默克密理博,FCMAB186F,Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	FITC	Monoclonal Antibody

描述
产品目录编号	FCMAB186F
商名	Milli-Mark
描述	Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1
Alternate Names	Membrane-spanning 4-domains subfamily A member 1<br />B-lymphocyte surface antigen B1<br />Leukocyte surface antigen Leu-16<br />Bp35<br />CD_antigen=CD20
背景信息	CD20 is a transmembrane, non-glycosylated protein expressed on B-cell precursors and mature B cells, but is lost following differentiation into plasma cells (Tedder, 1994). In resting B cells, CD20 appears in a 33 kDa non-phosphorylated form. After mitogen stimulation, CD20 becomes heavily phosphorylated (35-37 kDa isoforms), and it is a dominant phosphoprotein in activated B cells and B-cell lines (Zhou, 1995). The long N- and C-terminal ends of the protein are located on the cytoplasmic side of the membrane and only a minor portion of the protein is exposed on the cell surface (Tedder, 1994). Antibodies reacting with CD20 cytoplasmic epitopes are designated CD20cy (Zhou, 1995). It is suggested that CD20 plays a direct role in regulating the transmembrane conductive Ca 2+ flux of B cells which indicates a possible function for CD20 as a regulator of proliferation and differentiation (Tedder, 1994).

产品信息
格式	FITC
控制	Human Lymphocytes
演示	Purified Mouse monoclonal IgG1k conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2

应用
应用	This Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1 is validated for use in FC for the detection of CD20.
主要应用	Flow Cytometry

生物信息
克隆	B-Ly1
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Antibody recognizes Human CD20 antigen.
同种型	IgG1κ
品种反应性	Human
Species Reactivity Note	Tested and passed on Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_690605.1
纯化方法	Protein A purfied
UniProt编号	P11836

产品使用声明
质量保证	Evaluated by flow cytometry using human lymphocytes.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB186F,Milli-Mark Anti-CD20 -FITC Antibody, clone B-Ly1

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