merck millipore,默克密理愽
  • merck millipore,默克密理博,14-664,Mnk2 Protein, active, 10 µg

  • merck millipore,默克密理博,14-664,Mnk2 Protein, active, 10 µg

    产品名称：Mnk2 Protein, active, 10 µg
    产品型号：14-664
    Active, N-terminal 6His-tagged, recombinant, human, full length Mnk2, for use in Kinase Assays.

    merck millipore,默克密理博,14-664,Mnk2 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-664,Mnk2 Protein, active, 10 µg

    描述
    产品目录编号 14-664
    品牌系列 Upstate
    商名
    • Upstate
    描述 Mnk2 Protein, active, 10 µg
    概述 N-terminal 6His-tagged, recombinant, human, full length Mnk2
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, human, full length Mnk2, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_199054.2
    • NM_017572.3
    基因符号
    • MNK2
    • MKNK2
    • GPRK7
    • Mnk2
    蛋白靶 Mnk2
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CAMK
    UniProt编号
    • Q9HBH9
    UniProt汇总 FUNCTION: SwissProt: Q9HBH9 # May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
    COFACTOR: Magnesium. & Binds 1 zinc ion per subunit.
    SIZE: 465 amino acids; 51875 Da
    SUBUNIT: Monomer. Interacts with the C-terminal regions of EIF4G1 and EIF4G2. Also binds to dephosphorylated ERK1 and ERK2. Isoform 2 interacts with ESR2.
    TISSUE SPECIFICITY: Ubiquitously expressed in all tissues examined. Isoform 2 is expressed at higher levels in the ovary than is isoform 1.
    PTM: Dual phosphorylation of Thr-244 and Thr-249 activates the kinase. Phosphorylation of Thr-379 activates the kinase.
    SIMILARITY: SwissProt: Q9HBH9 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of MBP (Catalog # 13-104)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-664,Mnk2 Protein, active, 10 µg

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