merck millipore,默克密理博,FCMAB152F,Milli-Mark Anti-FXR1 -FITC Antibody, clone 6BG10

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	FITC	Monoclonal Antibody

描述
产品目录编号	FCMAB152F
商名	Milli-Mark
描述	Milli-Mark Anti-FXR1 -FITC Antibody, clone 6BG10
Alternate Names	fragile X mental retardation, autosomal homolog 1 <br />fragile X mental retardation-related protein 1
背景信息	Fragile X mental retardation-related protein 1 (FXR1) and FXR2 are members of the FMR1 family sharing a very high degree of protein similarity among them. They interact with each other and also with FMR1, moving between the cytoplasm and the nucleus. FXR1 is an RNA binding protein and is expressed in the heart, kidney, brain, and testis. Mutations in FMR1 result in the most common form of mental retardation.

产品信息
格式	FITC
控制	HeLa Cells
演示	Purified mouse monoclonal IgG2aκ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA

应用
应用	Milli-Mark Anti-FXR1 -FITC Antibody, clone 6BG10 is an antibody against FXR1 for use in FC.
主要应用	Flow Cytometry

生物信息
免疫原品种	Recombinant protein corresponding to human FXR1.
表位	Unknown
克隆	6BG10
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Antibody recognizes FXR1.
同种型	IgG2aκ
品种反应性	Human
Species Reactivity Note	Tested and passed on Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_001013456.1
Entrez基因汇总	The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
基因符号	hFXR1 FXR1
纯化方法	Protein G purfied
UniProt编号	P51114
UniProt汇总	FUNCTION: RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs By similarity. SUBUNIT STRUCTURE: Interacts with FMR1 and FXR2. Interacts with TDRD3, and with CYFIP2 but not with CYFIP1. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICTY: Expressed in all tissues examined including heart, brain, kidney and testis. PTM: Arg-445 is dimethylated, probably to asymmetric dimethylarginine. SEQUENCE SIMILARITIES: Belongs to the FMR1 family. Contains 2 KH domains

产品使用声明
质量保证	Evaluated by flow cytometry using using HeLa cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB152F,Milli-Mark Anti-FXR1 -FITC Antibody, clone 6BG10

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