merck millipore,默克密理愽
  • merck millipore,默克密理博,FCMAB144F,Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30

  • merck millipore,默克密理博,FCMAB144F,Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30

    产品名称：Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30
    产品型号：FCMAB144F
    Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30 is an antibody against RPA1 p70 for use in FC.

    merck millipore,默克密理博,FCMAB144F,Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30

  • 产品介绍
  • merck millipore,默克密理博,FCMAB144F,Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMFITCMonoclonal Antibody
    描述
    产品目录编号 FCMAB144F
    商名
    • Milli-Mark
    描述 Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30
    Alternate Names
    • RF-A protein 1 <br />RP-A p70 <br />Replication factor A protein 1 <br />Single-stranded DNA-binding protein <br />replication protein A 70 kDa DNA-binding subunit <br />replication protein A1 (70kD) <br />replication protein A1, 70kDa <br />replication protein A 70 kDa DNA-binding subunit <br />REPA1 <br />RPA1 <br />HSSB.
    背景信息 Replication protein A (RPA) is a multisubunit complex involved in DNA mismatch repair (MMR) in association with MSH2, MLH1 , PCNA, and DNA polymerase-delta. RPA is a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA1 p70 kDa is an ssDNA binding protein shown to be phosphorylated by ATM and ATR in response to DNA damage.RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.
    产品信息
    格式 FITC
    控制
    • HeLa Cells
    演示 Purified mouse monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
    应用
    应用 Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30 is an antibody against RPA1 p70 for use in FC.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 His-tagged recombinant protein corresponding to human RPA1.
    克隆 RPA9, 1-30
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody recognizes RPA1
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Tested and passed on Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002936
    基因符号
    • RPA70
    • RPA1
    • REPA1
    • RF-A
    • RP-A
    纯化方法 Protein G purfied
    UniProt编号
    • P27694
    UniProt汇总 FUNCTION: It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.

    SUBUNIT STRUCTURE: Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.

    SUBCELLULAR LOCATION: Nucleus.

    PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.

    SEQUENCE SIMILARITIES: Belongs to the replication factor A protein 1 family.
    产品使用声明
    质量保证 Tested by flow cytometry using HeLa Cells.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,FCMAB144F,Milli-Mark Anti-RPA1 p70 -FITC Antibody, clone RPA9, 1-30

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