merck millipore,默克密理博,FCABS352A4,Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	FC	Rb	AlexaFluor®488	Polyclonal Antibody

描述
产品目录编号	FCABS352A4
商名	Milli-Mark
描述	Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT
Alternate Names	Nanog homeobox Homeobox transcription factor Nanog
背景信息	NANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency, i.e., these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm). NANOG may be useful in the immunohistochemical diagnosis of tumors. NANOG is expressed in germ cells of the fetus and in some germ cell tumors of the gonads and central nervous system (CNS).

产品信息
格式	AlexaFluor®488
控制	2102 Ep cells
演示	Purified rabbit polyclonal IgG conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA

应用
应用	Milli-Mark Anti-Nanog-Alexa Fluor 488 Antibody, N-terminus is an antibody against Nanog-Alexa Fluor 488 for use in FC.
主要应用	Flow Cytometry

生物信息
免疫原品种	Linear peptide from mouse Nanog.
表位	N-terminus
宿主	Rabbit
特异性	Antibody recognizes NANOG.
同种型	IgG
品种反应性	RatHumanMouse
Species Reactivity Note	Tested and passed on Human. Predicted to react with Mouse, Rat based on 100% sequence homology.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_079141
基因符号	hNanog FLJ12581 FLJ40451
纯化方法	Antigen Affinity Purified
UniProt编号	Q9H9S0
UniProt汇总	Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor, when overexpressed, promotes cells to enter into S phase and proliferation.

产品使用声明
质量保证	Evaluated by flow cytometry using 2102 Ep cells
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCABS352A4,Milli-Mark™ Anti-Nanog-Alexa Fluor 488 Antibody, NT

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