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可用的分析物 品种反应性 主要应用 检测方法 Apo AIV H RIA Radioactive, Colorimetric 描述 产品目录编号 EZHAP0A4-73K 描述 Human Apo AIV ELISA 背景信息 Apolipoprotein AIV (Apo AIV) is a glycoprotein synthesized by the human intestine. Synthesis appears to be stimulated by the absorption of high density lipoproteins that are rich in triglycerides rather than by the uptake or re-esterification of fatty acids. The formation of chylomicrons acts as a signal for the induction of Apo AIV synthesis a signal enhanced by a factor from the ileum, probably PYY. Apo AIV alters the activity of the key enzymes (LPL and LCAT) of lipoprotein metabolism and cholesterol efflux from extrahepatic tissues. Also, since stimulation of intestinal synthesis and secretion by lipid absorption are rapid, Apo AIV likely plays a role in the short-term regulation of food intake. Other evidence suggests involvement in the long-term regulation of both food intake and body weight. Chronic ingestion of high-fat diet blunts the intestinal Apo AIV response to lipid feeding and, consequently, may explain why the chronic ingestion of a high-fat diet predisposes both animals and humans to obesity. 产品信息 检测方法 RadioactiveColorimetric 精度(%) - Intra-assay 4 – 6%
- Inter-assay 11 – 13%
应用 应用 This Human Apo AIV ELISA is used to measure & quantify Apo AIV levels in Metabolism research. 主要应用 - Radioimmunoassay
应用说明 This is a 4-hour assay at room temperature requiring 20 μL human serum, plasma, and tissue culture samples. 生物信息 特异性 The antibodies used in this kit show a high cross-reactivity to non-human primate samples. However, no species cross-reactivity is obseved in the assay to rat, mouse, canine, porcine, or sheep samples.
No cross reactivity was observed to the following human analytes:
Apo A1, Apo AII, Apo AV, Apo B, Apo CII, Apo CIII, Apo E, cytokines, adipokines or endocrine hormones.品种反应性 Human 可用的分析物 - Apo AIV
准确度 - 91-103%
理化信息 灵敏度 - 0.08 μg/mL
稀释的线性 85-117% 标准曲线范围 - 4.96 – 300 ng/mL
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well plate
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