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merck millipore,默克密理博,07-2119,Anti-phospho-RalA Antibody (Ser194)
产品名称:Anti-phospho-RalA Antibody (Ser194)
产品型号:07-2119
Detect the phospho-RalA (Ser194) protein using this Anti-phospho-RalA (Ser194) validated for use in WB & Peptide Inhibition Assay.
merck millipore,默克密理博,07-2119,Anti-phospho-RalA Antibody (Ser194)
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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Zebrafish, H, B, R, Xn WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-2119 描述 Anti-phospho-RalA Antibody (Ser194) Alternate Names - Ras-related protein Ral-A
背景信息 RalA and RalB are Ras-family small monomeric GTPases that can be activated through a Ras-dependent mechanism. The two are highly homologous (89%). Ral proteins are proximal effectors of oncogenic Ras and their activity is needed to support tumorigenesis in certain cancers. Mutants of Ras that are defective in activating all known Ras effectors except Ral GEF are still able to induce invasive phenotypes in transfected cells, suggesting a role for Ral in these processes. RalA is required for anchorage-independent proliferation and tumorigeneisis by driving exocyst assembly and polarized exocytosis in epithelial cells. 产品信息 格式 Affinity Purified 控制 - PANC10.05 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the phospho-RalA (Ser194) protein using this Anti-phospho-RalA (Ser194) validated for use in WB & Peptide Inhibition Assay. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A representative lot detected phospho-RalA (Ser194) in certain primary and metastatic cell lysates, and in certain unmatched tumor tissue lysate samples. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human RalA phosphorylated at Ser194. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes RalA phosphorylated at Ser194. 品种反应性 ZebrafishHumanBovineRatXenopus Species Reactivity Note Demonstrated to react with Human. Predicted to react with Bovine, Rat, Xenopus, and Zebrafish based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005393
基因符号 - Ral
- RALA
纯化方法 Affinity purified UniProt编号 - P11233
产品使用声明 质量保证 Evaluated by Western Blot in PANC10.05 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected phospho-RalA in PANC10.05 cell lysate. Peptide inhibition was observed with the addition of phospho peptides but not with the addition of non-phospho peptides.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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