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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC343 描述 Anti-Caspase-10 Antibody Alternate Names - Caspase-10
- Casp-10
背景信息 Caspase-10 is a member of the peptidase C14A family and is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is expressed in many tissues and cell lines with the lowest expression found in brain, kidney, prostate, testis, and colon. Mutations in Caspase-10 have been associated with autoimmune lymphoproliferative syndrome type 2A and gastric cancer. 产品信息 格式 Affinity Purified 控制 - HeLa, Jurkat, A431, and K562 whole cell lysates
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Detect Caspase 10 using this rabbit polyclonal antibody, Anti-Caspase-10 Antibody validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human Caspase-10. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the C-terminus of Caspase-10. 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - CASP10
纯化方法 Antigen Affinity purified UniProt编号 - Q92851
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa, Jurkat, A431, and K562 whole cell lysates.
Western Blotting Analysis: 1 µg/mL of this antibody detected Caspase-10 in 15 µg of HeLa, Jurkat, A431, and K562 whole cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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