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merck millipore,默克密理博,CBL555F,Anti-CD34 Class III Antibody, clone 581, FITC conjugated
产品名称:Anti-CD34 Class III Antibody, clone 581, FITC conjugated
产品型号:CBL555F
Detect CD34 Class III using this Anti-CD34 Class III Antibody, clone 581, FITC conjugated validated for use in FC.
merck millipore,默克密理博,CBL555F,Anti-CD34 Class III Antibody, clone 581, FITC conjugated
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M FITC Monoclonal Antibody 描述 产品目录编号 CBL555F 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-CD34 Class III Antibody, clone 581, FITC conjugated 产品信息 格式 FITC 演示 Protein G affinity chromatography. The conjugate is supplied as a 100 test vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test. 应用 应用 Detect CD34 Class III using this Anti-CD34 Class III Antibody, clone 581, FITC conjugated validated for use in FC. 主要应用 - Flow Cytometry
应用说明 Study of the Class III CD34 epitope by FACS
Optimal working dilutions must be determined by the end user.生物信息 克隆 581 宿主 Mouse 特异性 Clone 581 reacts with the class III CD34 epitope is resistant to neuraminidase, chymopapain and glycoprotease.
The antibody reacts with a single-chain 105-120 kDa heavily O-glycosylated transmembrane glycoprotein which is expressed on haematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. CD34 may also play a role in the adhesion of specific antigens to endothelium.同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001773.2
- NM_001025109.1
Entrez基因汇总 CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells.[supplied by OMIM] 基因符号 - CD34
UniProt编号 - P28906
UniProt汇总 FUNCTION: SwissProt: P28906 # Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
SIZE: 385 amino acids; 40716 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
DEVELOPMENTAL STAGE: On early hematopoietic progenitor cells.
PTM: Highly glycosylated. & Phosphorylated on serine residues by PKC.
DISEASE:SwissProt: P28906 # Abnormal CD34 expression in leukemogenesis.
SIMILARITY: SwissProt: P28906 ## Belongs to the CD34 family.产品使用声明 销售限制 This product is not available for sale in the United States. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C. 包装信息 数量 100 assays
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