merck millipore,默克密理博,512743,Pasteurella Multocida Toxin, Pasteurella multocida - CAS 129876-91-1

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merck millipore,默克密理博,512743,Pasteurella Multocida Toxin, Pasteurella multocida - CAS 129876-91-1 - Calbiochem
产品名称：Pasteurella Multocida Toxin, Pasteurella multocida - CAS 129876-91-1 - Calbiochem
产品型号：512743
A bacterial protein toxin that binds to and enters eukaryotic cells via receptor-mediated endocytosis.

merck millipore,默克密理博,512743,Pasteurella Multocida Toxin, Pasteurella multocida - CAS 129876-91-1 - Calbiochem

产品介绍

merck millipore,默克密理博,512743,Pasteurella Multocida Toxin, Pasteurella multocida - CAS 129876-91-1 - Calbiochem

重要规格表

CAS号
129876-91-1

描述
概述	A bacterial protein toxin that binds to and enters eukaryotic cells via receptor-mediated endocytosis. Acts intracellularly to initiate the inositol trisphosphate signaling pathway, Ca²⁺ mobilization, and DNA synthesis. Stimulates tyrosine phosphorylation of multiple substrates including focal adhesion kinase. Exerts its action on the α-subunit of the G_q family of G-proteins. Has been used for the activation of G_q-protein-coupled phosphatidylinositol-specific phospholipase C (PLC) in intact cells, making PMT useful as a tool for studying G_q-linked signal transduction.
产品目录编号	512743
品牌系列	Calbiochem®

参考
参考	Seo, B., et al. 2000. J. Biol. Chem. 275, 2239. Essler, M., et al. 1998. J. Immunol. 161, 5640. Wilson, B.A., et al. 1997. J. Biol. Chem. 272, 1268. Lacerda, H.M., et al. 1996. J. Biol. Chem. 271, 439. Foged, N.T. 1992. Acta Pathol. Microbiol. Immunol. Scand. 100 (Suppl. 25), 1. Staddon, J.M., et al. 1991. J. Biol. Chem. 266, 4840. Buys, W.E., et al. 1990. Nucleic Acids Res. 18, 2815. Lax, A.J., et al. 1990. FEBS Lett. 227, 59. Petersen, S.K. 1990. Mol. Microbiol. 4, 821. Foged, N.T., et al. 1987. FEMS Microbiol. Lett. 43, 45.

参考

Seo, B., et al. 2000. J. Biol. Chem. 275, 2239.
Essler, M., et al. 1998. J. Immunol. 161, 5640.
Wilson, B.A., et al. 1997. J. Biol. Chem. 272, 1268.
Lacerda, H.M., et al. 1996. J. Biol. Chem. 271, 439.
Foged, N.T. 1992. Acta Pathol. Microbiol. Immunol. Scand. 100 (Suppl. 25), 1.
Staddon, J.M., et al. 1991. J. Biol. Chem. 266, 4840.
Buys, W.E., et al. 1990. Nucleic Acids Res. 18, 2815.
Lax, A.J., et al. 1990. FEBS Lett. 227, 59.
Petersen, S.K. 1990. Mol. Microbiol. 4, 821.
Foged, N.T., et al. 1987. FEMS Microbiol. Lett. 43, 45.

产品信息
CAS号	129876-91-1
具有ATP竞争性	N
形式	Lyophilized solid
配方	Lyophilized from 100 mM NaCl, 30 mM Tris, 0.1% sucrose, pH 8.3.
Molar Mass	143000
可逆	N

生物信息
主靶	Acts intracellularly to initiate the inositol trisphosphate signaling pathway, Ca2+ mobilization, and DNA synthesis
纯度	Single band by SDS-PAGE

理化信息
细胞可渗透	N
溶解度	H₂O

安全信息
R相	R: 23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
S相	S: 36/37/39-45 Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Toxic
有害材料注意事项：	Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C or up to 2 weeks at 4°C.
加拿大出口规定	Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.