merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL304,Anti-Serum Amyloid P Antibody, clone 5.4A

  • merck millipore,默克密理博,CBL304,Anti-Serum Amyloid P Antibody, clone 5.4A

    产品名称：Anti-Serum Amyloid P Antibody, clone 5.4A
    产品型号：CBL304
    Anti-Serum Amyloid P Antibody, clone 5.4A detects level of Serum Amyloid P & has been published & validated for use in ELISA.

    merck millipore,默克密理博,CBL304,Anti-Serum Amyloid P Antibody, clone 5.4A

  • 产品介绍
  • merck millipore,默克密理博,CBL304,Anti-Serum Amyloid P Antibody, clone 5.4A

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HELISAMPurifiedMonoclonal Antibody
    描述
    产品目录编号 CBL304
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Serum Amyloid P Antibody, clone 5.4A
    Alternate Names
    • Component P
    背景信息 Amyloid consists mainly of rigid, non-branching protein fibrils, together with rod-like aggregates of a pentagonal-shaped glycoprotein called amyloid P protein. Amyloid P protein, also known as component P, comprises 10 per cent of amyloid tissue and is present in all but the central nervous system forms of amyloid. Amyloid P protein is a constituent of normal basement membranes and the microfibrillaryelastic fiber network.
    产品信息
    格式 Purified
    演示 The monoclonal is presented at a concentration of 100ug in phosphate buffered saline containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
    应用
    应用 Anti-Serum Amyloid P Antibody, clone 5.4A detects level of Serum Amyloid P & has been published & validated for use in ELISA.
    主要应用
    • ELISA
    应用说明 Development of ELISA assay for the estimation of human serum amyloid P using CBL 305 biotin conjugate as the labelled pair

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Human serum amyloid P
    克隆 5.4A
    宿主 Mouse
    特异性 This antibody is specific for human serum amyloid P.

    FUSION PARTNER: NS1 myeloma cell line
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001639.3
    Entrez基因汇总 The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
    基因符号
    • PTX2
    • SAP
    • SAMP
    • APCS
    UniProt编号
    • P02743
    UniProt汇总 FUNCTION: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
    COFACTOR: Binds 2 calcium ions per subunit.
    SUBUNIT: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
    SUBCELLULAR LOCATION: Secreted.
    TISSUE SPECIFICITY: Found in serum and urine.
    PTM: N-glycosylated with a complex biantennary oligosaccharide chain with a sialic acid at the end (disialo-SAP). Monosialo-SAP as well as asioalo-SAP are also detected.
    DISEASE: SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
    SIMILARITY: Belongs to the pentaxin family.
    SIMILARITY: Contains 1 pentaxin domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,CBL304,Anti-Serum Amyloid P Antibody, clone 5.4A

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