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merck millipore,默克密理博,CBL194F,Anti-Cytokeratin 7 Antibody, clone LP5K, FITC conjugated
产品名称：Anti-Cytokeratin 7 Antibody, clone LP5K, FITC conjugated
产品型号：CBL194F
Detect Cytokeratin 7 using this Anti-Cytokeratin 7 Antibody, clone LP5K, FITC conjugated validated for use in IC, IH, IH(P), FC.
merck millipore,默克密理博,CBL194F,Anti-Cytokeratin 7 Antibody, clone LP5K, FITC conjugated
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC, ICC, IHC M FITC Monoclonal Antibody 描述 产品目录编号 CBL194F 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Cytokeratin 7 Antibody, clone LP5K, FITC conjugated 产品信息 格式 FITC 演示 The antibody is ammonium sulphate precipitation followed by ion exchange chromatography. The conjugate is supplied in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. 应用 应用 Detect Cytokeratin 7 using this Anti-Cytokeratin 7 Antibody, clone LP5K, FITC conjugated validated for use in IC, IH, IH(P), FC. 主要应用 - Flow Cytometry
- Immunocytochemistry
- Immunohistochemistry
应用说明 Immunohistochemistry: Suitable for staining frozen sections and paraffin wax embedded tissue. Protease treatment of paraffin embedded sections is required prior to antibody application. Frozen sections (7 µm) of placental tissue fixed with acetone for 1 hr. Antibody used at 1:10 dilution (Sato et al., 2003).
Immunocytochemistry: isolated EVT cells fixed with 0.5% PFA at 4°C for 15 minutes followed by acetone at -20°C for 2 minutes. Antibody was used at 1:10 dilution (Sato et al., 2003).
Flow cytometry: 10μL of conjugate per test.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Cytoskeletal proteins from cultured HeLa cells 克隆 LP5K 宿主 Mouse 特异性 The antibody reacts with cytokeratin 7 which has been found in columnar and glandular epithelium of the lung, cervix, breast, bile ducts and larger collecting ducts of the kidney. Occasionally staining of blood vessel cell walls, particularly endothelial cells, may be observed.
FUSION PARTNER: Sp2/0同种型 IgG2b 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_005556.3
Entrez基因汇总 The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. 基因符号 - sarcolectin
- KRT7
- Sarcolectin
- Keratin-7
- K7
- MGC3625
- CK-7
- MGC129731
- SCL
- Cytokeratin-7
- K2C7
- CK7
UniProt编号 - P08729
UniProt汇总 FUNCTION: SwissProt: P08729 # Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
SIZE: 469 amino acids; 51418 Da
SUBUNIT: Heterotetramer of two type I and two type II keratins. Interacts with eukaryotic translation initiator factor 3 (eIF3) subunit EIF3S10 and with HPV16 E7.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.
PTM: Arg-20 is dimethylated, probably to asymmetric dimethylarginine.
SIMILARITY: SwissProt: P08729 ## Belongs to the intermediate filament family.
MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C for up to one year. 包装信息 数量 100 assays
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