merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL180F,Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated

  • merck millipore,默克密理博,CBL180F,Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated

    产品名称：Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated
    产品型号：CBL180F
    Detect E-Selectin using this Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated validated for use in FC.

    merck millipore,默克密理博,CBL180F,Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated

  • 产品介绍
  • merck millipore,默克密理博,CBL180F,Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Po, HFCMFITCMonoclonal Antibody
    描述
    产品目录编号 CBL180F
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated
    Alternate Names
    • CD62E
    • ELAM-1
    产品信息
    格式 FITC
    演示 The conjugate is supplied as a 100 test vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
    应用
    应用 Detect E-Selectin using this Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated validated for use in FC.
    主要应用
    • Flow Cytometry
    应用说明 Studies in a wide range of cell interactions in the vasculature together with diagnostic implications

    This antibody works in ELISA, immunohistology and also inhibits cellular adhesion

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 TNF-activated human umbilical vein endothelial cells
    克隆 1.2B6
    宿主 Mouse
    特异性 The antibody is specific to the human antigen E-selectin (ELAM-1, 115 kDa) that is expressed on activated endothelial cells. The ligand is expressed on neutrophils and may function as an early part in neutrophil binding to the endothelium.
    KNOWN SPECIES CROSS REACTIVITY: Recognizes porcine E-selectin
    同种型 IgG1
    品种反应性 PigHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000450.1
    Entrez基因汇总 The endothelial leukocyte adhesion molecule-1 is expressed by cytokine-stimulated endothelial cells. It is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. This gene is present in single copy in the human genome and contains 14 exons spanning about 13 kb of DNA. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
    基因符号
    • ELAM1
    • SELE
    • LECAM2
    • ESEL
    • ELAM
    • ELAM-1
    • CD62E
    UniProt编号
    • P16581
    UniProt汇总 FUNCTION: SwissProt: P16581 # Expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. The ligand recognized by ELAM-1 is sialyl-lewis X (alpha(1->3)fucosylated derivatives of polylactosamine that are found at the nonreducing termini of glycolipids).
    SIZE: 610 amino acids; 66655 Da
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    SIMILARITY: SwissProt: P16581 ## Belongs to the selectin/LECAM family. & Contains 1 C-type lectin domain. & Contains 1 EGF-like domain. & Contains 6 Sushi (CCP/SCR) domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C.
    包装信息
    数量 100 assays

    merck millipore,默克密理博,CBL180F,Anti-E-Selectin Antibody, clone 1.2B6, FITC conjugated

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下一件merck millipore产品：merck millipore,默克密理博,04-973,Anti-CD39 Antibody, clone 5F2


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