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merck millipore,默克密理博,CBL162P,Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated
产品名称:Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated
产品型号:CBL162P
Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated is an antibody against CD9 for use in FC.
merck millipore,默克密理博,CBL162P,Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Rb, H, M FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 CBL162P 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated Alternate Names - DRAP-27
- MRP-1
产品信息 格式 Phycoerythrin 演示 The conjugate is supplied as a 100 test vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test. 应用 应用 Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated is an antibody against CD9 for use in FC. 主要应用 - Flow Cytometry
应用说明 Characterization of leukaemias and lymphomas
Bone marrow purging in autologous bone marrow trans-plantation
Platelet inhibition and aggregation studies and association with CD41/CD61
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Human platelet glycoprotein 克隆 MM2/57 宿主 Mouse 特异性 This antibody reacts with a 25 kDa molecular weight band on gels of non-reduced platelet membranes and immunopre-cipitates a similar band from I125 labelled platelets. The antigen is expressed on eosinophils, granulocytes, monocytes and numerous stromal cells. This CD9 antigen belongs to the TM4 superfamily of cell surface proteins with the N- and C-terminals cytoplasmically located. This antibody reacts immuno-histochemically on frozen sections of platelets, monocytes and pre-B cells with differential staining on lymphoid and epithelial tissues.
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KNOWN SPECIES CROSS REACTIVITY: Positive with rabbit platelets and fibroblasts and mouse
FUSION PARTNER: NS1 myeloma cell line同种型 IgG2bκ 品种反应性 RabbitHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001769.2
Entrez基因汇总 The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance. 基因符号 - P24
- CD9
- Tspan-29
- MRP-1
- MIC3
- p24
- Tetraspanin-29
- BA2
- BTCC-1
- 5H9
- TSPAN29
- GIG2
- DRAP-27
UniProt编号 - P21926
UniProt汇总 FUNCTION: SwissProt: P21926 # Involved in platelet activation and aggregation. Regulates paranodal junction formation. Required for gamete fusion. Involved in cell adhesion, cell motility and tumor metastasis.
SIZE: 228 amino acids; 25416 Da
SUBUNIT: Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed by a variety of hematopoietic and epithelial cells.
PTM: Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids. & Phosphorylated on tyrosine following B-cell activation.
SIMILARITY: SwissProt: P21926 ## Belongs to the tetraspanin (TM4SF) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C. 包装信息 数量 100 assays
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