merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL1346Z-I,Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free)

  • merck millipore,默克密理博,CBL1346Z-I,Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free)

    产品名称：Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free)
    产品型号：CBL1346Z-I
    This Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free) is validated for use in Western Blotting, Immunoprecipitation, Flow Cytometry for the detection of mouse Integrin alphaV.

    merck millipore,默克密理博,CBL1346Z-I,Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free)

  • 产品介绍
  • merck millipore,默克密理博,CBL1346Z-I,Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free)

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MFC, WBRPurifiedMonoclonal Antibody
    描述
    产品目录编号 CBL1346Z-I
    Replaces CBL1346Z
    描述 Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free)
    Alternate Names
    • Integrin alphaV
    • Integrin alpha-V
    • Vitronectin receptor subunit alpha
    • CD51
    • 1.Integrin alpha-V heavy chain2.Integrin alpha-V light chain
    背景信息 Integrin alphaV, also known as CD51, a member of the integrin family, is a 140 kD protein expressed on activated T cells, polymorphonuclear granulocytes, blastocysts, and osteoclasts. Integrin alphaV forms heterodimers by association with integrins beta1, beta3, beta5 or beta6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The alphaV integrins have varied functions in development, stimulation/activation and homeostasis. The primary ligands for Integrin alphaV complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31.
    产品信息
    格式 Purified
    控制
    • Murine 3T3-L1 cells
    演示 Purified rat monoclonal IgG1κ in buffer containing PBS without preservatives.
    应用
    应用 This Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free) is validated for use in Western Blotting, Immunoprecipitation, Flow Cytometry for the detection of mouse Integrin alphaV.
    主要应用
    • Flow Cytometry
    • Western Blotting
    应用说明 Western Blot Analysis: A representative lot was used by an independent laboratory in LAK cell lysate. (Takahashi, K. et al., (1990). J. Immunol. 145:4371.)

    Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in LAK cell lysate. (Takahashi, K. et al., (1990). J. Immunol. 145:4371.)

    Blocking Assay: Adhesion and LAK cell cytotoxicity was shown using a representative lot (Takahashi, K. et al., (1990). J. Immunol. 145:4371.)
    生物信息
    免疫原品种 BALB/c mouse IL-2–activated killer (LAK) cells
    克隆 RMV-7
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rat
    特异性 Specifically recognizes Integrin alphaV, also known as CD51 or vitronectin receptor. This antibody has been reported to block binding of Integrin alphaV to vitronectin, fibronectin, fibrinogen, and CD31 in some cell types, as well as, blocking LAK cell cytotoxicity.
    同种型 IgG1κ
    品种反应性 Mouse
    Species Reactivity Note Demonstrated to react in Mouse.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_032428
    基因符号
    • Itgav
    纯化方法 Protein G purified
    UniProt编号
    • P43406
    产品使用声明
    质量保证 Evaluated by Flow Cytometry in murine 3T3-L1 cells.

    Flow Cytometry Analysis: 0.2 µg of this antibody detected Integrin alphaV in murine 3T3-L1 cells .
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,CBL1346Z-I,Anti-mouse Integrin alphaV Antibody, clone RMV-7 (Preservative free)

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下一件merck millipore产品：merck millipore,默克密理博,05-354,Anti-Clusterin α chain (human) Antibody, clone 41D


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