merck millipore,默克密理博,219373,Cathepsin G, Human Neutrophil

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merck millipore,默克密理博,219373,Cathepsin G, Human Neutrophil
产品名称：Cathepsin G, Human Neutrophil
产品型号：219373

merck millipore,默克密理博,219373,Cathepsin G, Human Neutrophil

产品介绍

merck millipore,默克密理博,219373,Cathepsin G, Human Neutrophil

描述
概述	Native cathepsin G from human neutrophil. A serine protease that degrades collagen and proteoglycans. Has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis. Acts as a potent agonist of human platelet activation leading to their aggregation. Reported to be involved in the activation of pro MMP-2 via mechanism requiring MT1-MMP. Inhibited by chymostatin, DFP, and Z-Phe-CH₂Br. Reconstitute in 150 mM NaCl, 50 mM sodium acetate buffer, pH 5.5.
概述	Note: 1 mU = 1 milliunit.
产品目录编号	219373
品牌系列	Calbiochem®

参考
参考	Glusa, E., and Adam C. 2001. Por. J. Pharmacol. 133, 422. Shamamian, P., et al. 2001. J. Cell Physiol. 189, 197. Groutas, W.C., et al. 1993. Biochem. Biophys. Res. Commun. 197, 730. Stone, P.J., et al. 1993. Biochem. Biophys. Res. Commun. 197, 130. Groutas, W.C., et al. 1992. Arch. Biochem. Biophys. 294, 144. Maison, C.M., et al. 1991. J. Immunol. 147, 921. Travis, J. 1988. Am. J. Med. 84, 37.

参考

Glusa, E., and Adam C. 2001. Por. J. Pharmacol. 133, 422.
Shamamian, P., et al. 2001. J. Cell Physiol. 189, 197.
Groutas, W.C., et al. 1993. Biochem. Biophys. Res. Commun. 197, 730.
Stone, P.J., et al. 1993. Biochem. Biophys. Res. Commun. 197, 130.
Groutas, W.C., et al. 1992. Arch. Biochem. Biophys. 294, 144.
Maison, C.M., et al. 1991. J. Immunol. 147, 921.
Travis, J. 1988. Am. J. Med. 84, 37.

产品信息
CAS号	107200-92-0
EC号	3.4.21.20
形式	Salt-free lyophilized solid
Molar Mass	23500

生物信息
纯度	≥95% by SDS-PAGE
来源	Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
特异活性	≥2 units/mg protein

理化信息
pH值	optimum 7.5
溶解度	100mM NaCl, 50 mM Sodium acetate, pH 5.5.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 6 months at -70°C.