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描述 产品目录编号 AG345 品牌系列 Chemicon®
商名 - Chemicon
描述 Na+/H+ Exchanger-1, Control Peptide for AB3081/AB3082 概述 Na+/H+ Exchanger 1 (NHE1) control peptide. 产品信息 演示 Liquid in PBS, pH 7.5. 应用 主要应用 - Peptide Inhibition Assay
应用说明 Antibody blocking (AB3081/AB3082)
Optimal working concentration must be determined by the end user.生物信息 浓缩 1 mg/mL 品种 Rat Entrez基因编号 - NM_003047.2
基因符号 - APNH1
- SLC9A1
- FLJ42224
- APNH
- NHE-1
- Na
- +H
- NHE1
UniProt编号 - P19634
UniProt汇总 FUNCTION: SwissProt: P19634 # Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
SIZE: 815 amino acids; 90763 Da
SUBUNIT: Interacts with tescalcin, CHP and CHP2.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Kidney and intestine.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. & O-glycosylated.
SIMILARITY: SwissProt: P19634 ## Belongs to the Na(+)/H(+) exchanger (TC 2.A.36.5.1) family.
MISCELLANEOUS: Inhibited by amiloride and 5-amino-substituted derivatives and activated in a cooperative fashion by intracellular H(+). In quiescent cells upon growth factor stimulation, the apparent affinity for internal H(+) is increased, resulting in a persistent rise in cytoplasmic pH.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,08-115,Collagen Type I, rat tail
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