merck millipore,默克密理博,AG230,Glial Fibrillary Acidic Protein, porcine

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merck millipore,默克密理博,AG230,Glial Fibrillary Acidic Protein, porcine
产品名称：Glial Fibrillary Acidic Protein, porcine
产品型号：AG230

merck millipore,默克密理博,AG230,Glial Fibrillary Acidic Protein, porcine

产品介绍

merck millipore,默克密理博,AG230,Glial Fibrillary Acidic Protein, porcine

描述
产品目录编号	AG230
品牌系列	Chemicon®
商名	Chemicon
描述	Glial Fibrillary Acidic Protein, porcine
概述	Purified porcine Glial Fibrillary Acidic Protein (GFAP) purified from spinal cord.
Alternate Names	GFAP

产品信息
演示	Liquid. Buffer = PBS.

应用
主要应用	ELISA Western Blotting
应用说明	Western blotting Protein standard ELISA Radioimmunoassay Optimal working dilution must be determined by the end user.

生物信息
浓缩	~330 μg/mL
纯度	Contains >98% pure GFAP, a 50 kDa single band by SDS-PAGE.
品种	Porcine
Entrez基因编号	NM_002055.2
Entrez基因汇总	This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined.
基因符号	FLJ45472 GFAP
UniProt编号	P14136
UniProt汇总	FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. SIZE: 432 amino acids; 49880 Da SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1. SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments. DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander disease [MIM:203450]. Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. The most common form affects infants and young children, and is characterized by progressive failure of central myelination, usually leading to death usually within the first decade. Infants with Alexander disease develop a leukoencephalopathy with macrocephaly, seizures, and psychomotor retardation. Patients with juvenile or adult forms typically experience ataxia, bulbar signs and spasticity, and a more slowly progressive course. SIMILARITY: SwissProt: P14136 ## Belongs to the intermediate filament family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at -20°C to -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.

储存和货运信息

存储条件

Maintain at -20°C to -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.