merck millipore,默克密理博,ABT157,Anti-Syndecan-4 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABT157
描述	Anti-Syndecan-4 Antibody
Alternate Names	Ryudocan core protein SYND4 Amphiglycan
背景信息	Syndecan-4 (Amphiglycan; Ryudocan core protein) is one of four members of the syndecan proteoglycan family. The syndecan proteins bind heparan sulfate and mediate the signaling of growth factors, such as fibroblast growth factor, that recognize and bind heparan chains. Unlike other members of this family, syndecan-4 is ubiquitously expressed, and is targeted to focal adhesions, possibly by a PKC-mediated pathway. Previous studies have reported an increase in focal adhesions in cells overexpressing syndecan-4. This protein also plays an important role in wound healing, by modulating the signaling of Rho-GTPases Rac1, RhoG, and RhoA.

产品信息
格式	Affinity Purified
控制	HEP2 cell lysate
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	This Anti-Syndecan-4 Antibody is validated for use in Western Blotting, IHC(P) for the detection of Syndecan-4.
主要应用	Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:100-1,000 dilution from a representative lot detected Syndecan-4 in human lung carcinoma and in distal tubules of normal human kidney tissue.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Syndecan-4.
表位	Cytoplasmic domain
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody recognizes the cytoplasmic domain of Syndecan-4
品种反应性	RatHumanMouse
Species Reactivity Note	Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine, Chimpanzee, and Rhesus Macaque based on 100% sequence homology.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_002990
基因符号	SDC4
纯化方法	Affinity purified
UniProt编号	P31431

产品使用声明
质量保证	Evaluated by Western Blot in HEP2 cell lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Syndecan-4 in 10 µg of HEP2 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABT157,Anti-Syndecan-4 Antibody

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