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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 ABT142 描述 Anti-PLK-4 Antibody Alternate Names - Serine/threonine-protein kinase Sak
- Serine/threonine-protein kinase PLK4
- Polo-like kinase 4
- PLK-4
- Serine/threonine-protein kinase 18
背景信息 Serine/threonine-protein kinase PLK4 (PLK-4) is a member of the protein kinase superfamily and plays an essential role in centriole duplication. PLK-4 triggers procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins. It may be involved in tumorigenesis since centrosome aberrations are frequently observed in tumors. PLK-4 may also be involved in trophoblast differentiation by phosphorylating HAND1, leading to the disruption between HAND1 and MDFIC and then activating HAND1. 产品信息 格式 Purified 控制 - Jurkat cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-PLK-4 Antibody detects level of PLK-4 & has been published & validated for use in Western Blotting, ICC. 主要应用 - Immunocytochemistry
- Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the POLO box domain of human PLK-4. 表位 POLO box domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the POLO box domain of PLK-4 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_0055079
基因符号 - STK18
- PLK4
- SAK
纯化方法 Protein A purified UniProt编号 - O00444
产品使用声明 质量保证 Evaluated by Western Blot in Jurkat cell lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected PLK-4 in 10 µg of Jurkat cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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