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品种反应性 主要应用 宿主 格式 抗体类型 R, M ELISA, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT123 Replaces AB755P 描述 Anti-Collagen Type I Antibody Alternate Names - Alpha-1 type I collagen
- Collagen alpha-1(I) chain
背景信息 Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. 产品信息 格式 Affinity Purified 控制 - Rat skin tissue
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Collagen Type I using this Anti-Collagen Type I Antibody validated for use in Western Blotting, IHC(P), ELISA. 主要应用 - ELISA
- Western Blotting
应用说明 Specificity ELISA Analysis: A representative lot detected mouse and rat collagen but not human collagen in ELISA.
Western Blot Analysis: A 1:2,000 dilution from a representative lot detected Collagen Type 1 on 10 µg of rat skin tissue lysate.生物信息 免疫原品种 Rat tail collagen 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatMouse Species Reactivity Note Demonstrated to react with Rat and Mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_445756
基因符号 - COL1A1
纯化方法 Affinity purified UniProt编号 - P02452
产品使用声明 质量保证 Evaluated by Immunohistochemistry in rat skin tissue.
Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Collagen Type 1 in rat skin tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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