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merck millipore,默克密理博,208293,Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - Calbiochem
产品名称：Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - Calbiochem
产品型号：208293
The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel.
merck millipore,默克密理博,208293,Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₈H₂₁NO₄S 描述 概述 An aminothiophene that inhibits Calcium-activated Chloride Channel (CaCC) current influx induced by multiple calcium-elevating agonists (IC50 = 10 µM) without inhibiting calcium elevation, and CaMKII and CFTR activity. Inhibits CaCC chloride response following agonist stimulation in human bronchial and intestinal epithelial cells. Also demonstrates an inhibitory effect on TMEM16A channels (IC50 = 2.1 µM). Also available as a 100 mM solution in DMSO (Cat. No. 508628). 产品目录编号 208293 品牌系列 Calbiochem®
同义词 6-tert-butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid, CaCC Blocker I, TMEM16 Blocker I, ANO Blocker I, Anoctamin Blocker I 参考 参考 Fuente, R., et al. 2011, Mol Pharmacol. 73, 758.
Namkung, W., et al. 2011, J Biol Chem. 286, 2365.产品信息 形式 Off-white solid Hill配方 C₁₈H₂₁NO₄S 化学配方 C₁₈H₂₁NO₄S Molar Mass 347.43 结构配方图像 生物信息 纯度 ≥98% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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