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merck millipore,默克密理博,ABE539,Anti-acetyl Histone H3 Antibody (Lys 14)
产品名称:Anti-acetyl Histone H3 Antibody (Lys 14)
产品型号:ABE539
Anti-acetyl Histone H3 Antibody (Lys 14) is a highly specific rabbit polyclonal antibody, that targets Histone H3 & has been tested in western blotting & Chromatin IP (ChIP).
merck millipore,默克密理博,ABE539,Anti-acetyl Histone H3 Antibody (Lys 14)
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Yeast, H ChIP, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 ABE539 Replaces 04-1044 描述 Anti-acetyl Histone H3 Antibody (Lys 14) Alternate Names - Histone H3
背景信息 Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. The term "Histone H3" alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state. Histone H3 is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. 产品信息 格式 Serum 演示 Rabbit polyclonal serum containing 0.002% Thimerosal. 应用 应用 Anti-acetyl Histone H3 Antibody (Lys 14) is a highly specific rabbit polyclonal antibody, that targets Histone H3 & has been tested in western blotting & Chromatin IP (ChIP). 主要应用 - Chromatin Immunoprecipitation (ChIP)
- Western Blotting
应用说明 Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected acetyl Histone H3 (Lys14) in sodium butyrate treated HeLa acid extract and demonstrated a loss of signal in untreated HeLa acid extract.
Western Blotting Analysis: A representative lot from an independent laboratory detected acetyl Histone H3 (Lys14) in WT and certain mutant Histones H4, H2B, H3, and H2A (Suka, N., et al. (2001). Mol Cell. 8(2):473-479.).
Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated acetyl Histone H3 (Lys14) in WT and certain mutant Histones H4, H2B, H3, and H2A (Suka, N., et al. (2001). Mol Cell. 8(2):473-479.).生物信息 免疫原品种 Ovalbumin-conjugated linear peptide corresponding to yeast Histone H3 acetylated at Lys14. 宿主 Rabbit 品种反应性 YeastHuman Species Reactivity Note Demonstrated to react with Human and Yeast. Predicted to react with Mouse and Rat based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_009564
基因符号 - SIN2
- HHT1
- HHT2
修改 - Acetylation
纯化方法 Unpurified UniProt编号 - P61830
产品使用声明 质量保证 Evaluated by Western Blotting in etoposide treated HL-60 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected acetyl Histone H3 (Lys14) in etoposide treated HL-60 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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