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merck millipore,默克密理博,ABS88,Anti-phospho-mTOR (Thr2164) Antibody
产品名称：Anti-phospho-mTOR (Thr2164) Antibody
产品型号：ABS88
Anti-phospho-mTOR (Thr2164) Antibody is an antibody against phospho-mTOR (Thr2164) for use in Dot Blot, Western Blotting.
merck millipore,默克密理博,ABS88,Anti-phospho-mTOR (Thr2164) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 ABS88 描述 Anti-phospho-mTOR (Thr2164) Antibody Alternate Names - Rapamycin target protein 1
- Serine/threonine-protein kinase mTOR
- FK506-binding protein 12-rapamycin complex-associated protein 1
- FKBP12-rapamycin complex-associated protein
- Mammalian target of rapamycin
- mTOR
- Mechanistic target of rapamycin
- Rapamycin and FKBP12 target 1
背景信息 The mammalian target of rapamycin (mTOR), also known as FRAP, RAFT, or RAPT, is a ubiquitously expressed serine/threonine kinase that belongs to the phosphoinositide 3-kinase–related kinase (PIKK) family. mTOR functions as a downstream effector in the PI3K pathway and is activated by the Akt kinase. mTOR responds to signals from growth factors and promotes protein synthesis underlying cell proliferation, by activation of the S6 kinase and inhibition of the 4E-BP protein involved in protein translation. Several studies have suggested that the proliferative functions of mTOR may contribute to the development of cancer. 产品信息 格式 Serum 控制 - Unmodified and phosphorylated mTOR peptides
演示 Rabbit polyclonal serum containing 0.05% sodium azide. 应用 应用 Anti-phospho-mTOR (Thr2164) Antibody is an antibody against phospho-mTOR (Thr2164) for use in Dot Blot, Western Blotting. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A representative lot was used by an independent laboratory in HEK293 cell lysate. (Ekim, B., et al. (2011). MCB. [Epub ahead of print].) 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human mTOR phosphorylated at Thr2164. 表位 Phosphorylated Thr2164 宿主 Rabbit 特异性 This antibody recognizes mTOR phosphorylated at Thr2164. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_004949
基因符号 - RAPT1
- MTOR
- FRAP
- FRAP1
- FRAP2
- RAFT1
纯化方法 Unpurified UniProt编号 - P42345
产品使用声明 质量保证 Dot Blot Specificity Analysis: Unmodified and phosphorylated mTOR peptides were probed with Anti-phospho-mTOR (Thr2164) (1:1,000 dilution). 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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