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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M IHC, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 07-601 Replaces MABE513 品牌系列 Upstate
商名 - Upstate
描述 Anti-TTF-1 Antibody 产品信息 格式 Serum 演示 rabbit antiserum containing 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Anti-TTF-1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of TTF-1 & has been validated in IP, WB & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
生物信息 免疫原品种 6His fusion protein corresponding to full-length TTF-1 (Thyroid transcription factor 1, also known as Thyroid nuclear factor 1, Homeobox protein Nkx-2.1) 宿主 Rabbit 特异性 TTF-1 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003317.3
基因符号 - TITF1
- TTF1
- TTF-I
- NKX2A
纯化方法 Serum UniProt编号 - P43699
UniProt汇总 FUNCTION: SwissProt: P43699 # Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis.
SIZE: 371 amino acids; 38596 Da
TISSUE SPECIFICITY: Thyroid and lung.
SUBCELLULAR LOCATION: Nucleus
DISEASE: Defects in NKX2-1 are the cause of choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD) [MIM:610978]. This syndrome include neurological, thyroid, and respiratory problems.
PTM: Phosphorylated on serine residues
SIMILARITY: Belongs to the NK-2 homeobox family.产品使用声明 质量保证 routinely evaluated by immunoblot on nuclear extract from H441 human lung epithelial cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µL
上一件merck millipore产品：merck millipore,默克密理博,09-471,Anti-phospho-CLASP1 (Ser600) Antibody
下一件merck millipore产品：merck millipore,默克密理博,440153,L-α-lysophosphatidylinositol Sodium Salt, Soy - CAS 796963-91-2 - Calbiochem
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