merck millipore,默克密理博,ABS605,Anti-FABP2 Antibody

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merck millipore,默克密理博,ABS605,Anti-FABP2 Antibody
产品名称：Anti-FABP2 Antibody
产品型号：ABS605
Anti-FABP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Fatty Acid Binding Protein & has been tested in western blotting.

merck millipore,默克密理博,ABS605,Anti-FABP2 Antibody

产品介绍

merck millipore,默克密理博,ABS605,Anti-FABP2 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABS605
Replaces	MABS390; MABS401
描述	Anti-FABP2 Antibody
Alternate Names	FABP2 Fatty acid-binding protein, intestinal Fatty acid-binding protein 2 Intestinal-type fatty acid-binding protein I-FABP
背景信息	Fatty acid-binding protein 2, (FABP2) is produced by the intestinal tissues of the small intestine and participates in the transport and intracellular internalization and metabolism of fatty acids in the gut. Its expression is localized to the small intestine, especially within the cellular epithelial cells of the jejunum, with much lower levels in the large intestine. FBAP2 is confined to the cytoplasm and induced by growth factors such as EGF. FABP2 is also known as FABPI or I-FABP. Because of its role in fatty acid uptake and lipid homeostasis, mutations or polymorphisms affecting the function of FABP2 in fatty acid metabolism have been a source of recent research. In particular, an amino acid substitution known as A54T where the G to A polymorphism of codon 54 of the FABP2 gene results in the substation of a Thr in the mutated form instead of an Ala in the normal form. This Thr-codon 54 mutation demonstrates an increased affinity for long-chain fatty acids and is strongly associated with factors associated with metabolic syndrome disease, including insulin resistance, enhanced fatty acid oxidation, elevated triglycerides and type 2 diabetes. Furthermore, FABPs and in particular , FABP2, play an increasingly important role in controlling the lipid signaling cascade and is being studied as key regulatory factor of lipid signaling under normal and pathological conditions.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Anti-FABP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Fatty Acid Binding Protein & has been tested in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	GST-tagged fusion protein corresponding to human FABP2.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Mouse
抗体类型	Polyclonal Antibody
基因符号	FABPI FABP2
纯化方法	Antigen Affinity purified
UniProt编号	P12104

产品使用声明
质量保证	Evaluated by Western Blotting in mouse small intestine tissue lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected FABP2 in mouse small intestine tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.