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品种反应性 主要应用 宿主 格式 抗体类型 H, M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS586 描述 Anti-GUSB Antibody Alternate Names - GUSB
- Beta-glucuronidase
- Beta-G1
背景信息 The protein Beta glucuronidase or Beta-G1 and encoded by the human gene GUSB is lysosomal protein involved in the degradation of keratan, heparan, and chondroitin sulfates (including other glycosaminoglycans). Glycosaminoglycans are composed of sugar molecules that are linked together to form a long string. To break down these large molecules, individual sugars are removed one at a time from one end of the molecule. GUSB enzyme removes a sugar called glucuronic acid when it is at the end of the glycosaminoglycan chain. Defects in GUSB lead to various lysosomal storage diseases and a buildup of dermatan, heparan, and chondroitin sulfates within cells that disrupt normal cell function. EMD-Millipore’s Anti-GUSB rabbit polyclonal antibody has been tested in western blot on mouse liver tissue and in paraffin embedded human colon cancer tissue sections. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect Beta glucuronidase using this rabbit polyclonal antibody, Anti-GUSB Antibody validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected GUSB in human colon cancer tissue. 生物信息 免疫原品种 GST-tagged fusion protein corresponding to human GUSB. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 HumanMouse Species Reactivity Note Mouse, Human 抗体类型 Polyclonal Antibody 基因符号 - GUSB
纯化方法 Antigen Affinity purified UniProt编号 - P08236
产品使用声明 质量保证 Evaluated by Western Blotting in mouse liver tissue lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected GUSB in mouse liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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