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品种反应性 主要应用 宿主 格式 抗体类型 M, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS583 描述 Anti-AMH Antibody Alternate Names - MIS
- AMH
- Muellerian-inhibiting factor
- Anti-Muellerian hormone
- Muellerian-inhibiting substance
背景信息 The protein named Muellerian-inhibiting factor or alternatively Anti-Muellerian hormone (AMH) or Muellerian inhibiting substance (MIS), and encoded by the human gene named AMH or MIF, is a hormone like glycoprotein. AMH is produced by the Sertoli cells of the testis, and AMH causes regression of the Muellerian duct. AMH is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. The Müllerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the Müllerian eminence in the primitive urogenital sinus. In the female, they will develop to form the Fallopian tubes, uterus, cervix, and the upper two-thirds of the vagina. In the male, they are lost because of the action of AMH. AMH is expressed in the developing and adult testis and in the ovary in females where it functions in oocyte maintenance. Interestingly recent research has shown promise that levels of AMH in the blood can be used as a potential guide for the health of the ovarian reserve in women over 40, and AMH appears critical for IVF treatment in women over 40. EMD-Millipore’s Anti-AMH rabbit polyclonal antibody has been tested in western blot on mouse ovary tissue and in paraffin embedded immunohistochemistry on human ovary tumor tissue sections. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-AMH Antibody is a highly specific rabbit polyclonal antibody, that targets Muellerian-inhibiting factor & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:25 dilution from a representative lot detected AMH in human ovary tumor tissue. 生物信息 免疫原品种 Histidine-tagged fusion protein corresponding to human AMH. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody 基因符号 - MIF
- AMH
纯化方法 Antigen Affinity purified UniProt编号 - P03971
产品使用声明 质量保证 Evaluated by Western Blotting in mouse ovary tissue lysate.
Western Blotting Analysis: A 1:300 dilution of this antibody detected AMH in mouse ovary tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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