merck millipore,默克密理愽
  • merck millipore,默克密理博,182800,Ascomycin, Streptomyces hygroscopicus - CAS 11011-38-4 - Calbiochem

  • merck millipore,默克密理博,182800,Ascomycin, Streptomyces hygroscopicus - CAS 11011-38-4 - Calbiochem

    产品名称：Ascomycin, Streptomyces hygroscopicus - CAS 11011-38-4 - Calbiochem
    产品型号：182800
    An ethyl analog of FK506 with similar immunosuppressant properties.

    merck millipore,默克密理博,182800,Ascomycin, Streptomyces hygroscopicus - CAS 11011-38-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,182800,Ascomycin, Streptomyces hygroscopicus - CAS 11011-38-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₄₃H₆₉NO₁₂11011-38-4
    描述
    概述 An ethyl analog of FK506 with similar immunosuppressant properties. Acts by binding to immunophilins. Inhibits the synthesis of Th-1 and Th-2 type cytokines in target cells.
    产品目录编号 182800
    品牌系列 Calbiochem®
    同义词 Immunomycin, FR-900520
    参考
    参考 Paul, C., et al. 2000. Expert Opin. Invest. Drugs 9, 69.
    Kawai, M., et al. 1993. FEBS Lett. 316, 107.
    Pilot-Matias, T.J., et al. 1993. Gene 128, 219.
    Shafiee, A., et al. 1993. J. Antibiot. 46, 1397.
    Petros, A.M., et al. 1992. J. Med. Chem. 35, 2467.
    产品信息
    CAS号 11011-38-4
    具有ATP竞争性 N
    形式 White crystalline solid
    Hill配方 C₄₃H₆₉NO₁₂
    化学配方 C₄₃H₆₉NO₁₂
    Molar Mass 792.0
    可逆 N
    结构配方图像
    生物信息
    生物活性 Fully active via yeast rotamase (FK 506 binding protein) inhibition
    主靶 Immunophilins
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or EtOH
    GHS安全信息
    RTECS CI7570000
    安全信息
    R相 R: 20/21/22-36/37/38

    Harmful by inhalation, in contact with skin and if swallowed.
    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Ethanol stock solutions are stable for up to 3 days at -20°C. Anhydrous DMSO stock solutions are stable for up to 1 month -20°C.

    merck millipore,默克密理博,182800,Ascomycin, Streptomyces hygroscopicus - CAS 11011-38-4 - Calbiochem

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