merck millipore,默克密理博,ABS524,Anti-Lipin-2 Antibody

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merck millipore,默克密理博,ABS524,Anti-Lipin-2 Antibody
产品名称：Anti-Lipin-2 Antibody
产品型号：ABS524
Anti-Lipin-2 Antibody is an antibody against Lipin-2 for use in western blotting, IHC & IP.

merck millipore,默克密理博,ABS524,Anti-Lipin-2 Antibody

产品介绍

merck millipore,默克密理博,ABS524,Anti-Lipin-2 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABS524
描述	Anti-Lipin-2 Antibody
Alternate Names	Lipin-2 Phosphatidate phosphatase LPIN2
背景信息	Lpin2, also known as Phosphatidate phosphatase LPIN2, and encoded by the gene Lpin2, plays important roles in controlling the metabolism of fatty acids. Lpin2 acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Lpin2 also acts as a nuclear transcriptional coactivator for PGC-1α protein. Lpin2 is localized to the cytoplasm and endoplasmic reticulum membrane but is also found in the nucleus. Lpin2 is expressed in many cells and tissues including liver, lung, kidney, placenta, prostate, and intestine. Expression is also seen in RBCs and at sites of lymphopoiesis in bone and spleen. Homozygous mutations in LPIN2 result in Majeed syndrome. Majeed syndrome is an autosomal recessive, autoinflammatory disorder characterized by chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anemia.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide with 50% glycerol.

应用
应用	Anti-Lipin-2 Antibody is an antibody against Lipin-2 for use in western blotting, IHC & IP.
主要应用	Immunohistochemistry Western Blotting
应用说明	Western Blotting Analysis: A representative lot detected Lipin-2 in mouse WAT cell lysate (Gropler, M. C., et al. (2008). JBC. 284(11):6763-6772). Immunocytochemistry Analysis: A representative lot detected Lipin-2 in mouse cerebellum tissue (Mayurranjan, S., et al. (2013). PNAS. 110(2):642-647).

生物信息
免疫原品种	Linear peptide corresponding to mouse Lipin-2.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Mouse
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_075020
基因符号	Lpin2
纯化方法	Affinity purified
UniProt编号	Q99PI5

产品使用声明
质量保证	Evaluated by Western Blotting in mouse hepatocytes cell lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected Lipin-2 in 10 µg of mouse hepatocytes cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.