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merck millipore,默克密理博,390900,4-Hydroxyphenylretinamide - CAS 65646-68-6 - Calbiochem
产品名称：4-Hydroxyphenylretinamide - CAS 65646-68-6 - Calbiochem
产品型号：390900
A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity.
merck millipore,默克密理博,390900,4-Hydroxyphenylretinamide - CAS 65646-68-6 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₆H₃₃NO₂ 65646-68-6 描述 概述 A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity. Active in the prevention and treatment of a variety of neoplasms in animals. Inhibits human breast cancer, prostate adenocarcinoma, and ovarian carcinoma cell proliferation. Inhibits angiogenesis as well as endothelial cell motility and tubule formation. Induces apoptosis in malignant hemopoietic cell lines. 产品目录编号 390900 品牌系列 Calbiochem®
同义词 Fenretinide, 4HPR, N-(4-Hydroxyphenyl)-all-trans Retinamide 参考 参考 Formelli, F., et al. 1996. FASEB J. 10, 1014.
Naik, H.R., et al. 1995. Adv. Pharmacol. 33, 315.
Delia, D., et al. 1993. Cancer Res. 53, 6036.
Pienta, K.J., et al. 1993. Cancer Res. 53, 224.
Grubbs, C.J., et al. 1990. Anticancer Res. 10, 661.
McCarthy, D.J., et al. 1987. Cancer Res. 47, 5014.
Moon, R.C., et al. 1979. Cancer Res. 39, 1339.产品信息 CAS号 65646-68-6 具有ATP竞争性 N 形式 Orange solid Hill配方 C₂₆H₃₃NO₂ 化学配方 C₂₆H₃₃NO₂ Molar Mass 391.6 可逆 N 结构配方图像 生物信息 主靶 Active in the prevention and treatment of a variety of neoplasms in animals. 纯度 ≥97% by TLC 理化信息 细胞可渗透 N 溶解度 DMSO or EtOH GHS安全信息 RTECS VH6420000 安全信息 R相 R: 20/21/22-36/37/38-60-61
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
May impair fertility.
May cause harm to the unborn child.S相 S: 26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful & Carcinogenic / Teratogenic
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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