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merck millipore,默克密理博,ABS481,Anti-phospho Beta Catenin (Ser675) Antibody
产品名称：Anti-phospho Beta Catenin (Ser675) Antibody
产品型号：ABS481
Anti-phospho Beta Catenin (Ser675) Antibody is a highly specific rabbit polyclonal antibody, that targets Catenin & has been tested in western blotting & Peptide Inhibition Assay.
merck millipore,默克密理博,ABS481,Anti-phospho Beta Catenin (Ser675) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS481 描述 Anti-phospho Beta Catenin (Ser675) Antibody Alternate Names - Beta-catenin
- Catenin beta-1
背景信息 β-catenin plays a central role in cell adhesion, bridging between cadherins and actin cytoskeleton. These activities are regulated through its differential interaction with several molecular partners, including cell-cell adherens junction (AJ) molecules, components of its degradation complex, and transcription factors. β-Catenin is composed of three domains: a central armadillo repeat domain and two N- and C-terminal tails. β-catenin can be phosphorylated by serine-threonine kinase, such as GSK-3. The phosphorylated β-catenin affects the protein association of β-catenin to E-cadherin and α-cateinin that occurs in the cell. This process can be reversed by de-phosphorylation of β-catenin. 产品信息 格式 Affinity Purified 控制 - SW480 cell lysates
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-phospho Beta Catenin (Ser675) Antibody is a highly specific rabbit polyclonal antibody, that targets Catenin & has been tested in western blotting & Peptide Inhibition Assay. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to a region near the C-terminus of human Beta Catenin phosphorylated at Ser675. 表位 Near C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes a region near the C-terminus of Beta Catenin phosphorylated at Ser675. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse, Rat, Chicken, Canine, Xenopus, Zebrafish based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001895
基因符号 - CTNNB
- CTNNB1
纯化方法 Affinity purified UniProt编号 - P35222
产品使用声明 质量保证 Evaluated by Western Blotting/Peptide Inhibition Analysis in SW480 cell lysates.
Western Blotting/Peptide Inhibition Analysis: A 1:500 dilution from a representative lot, incubated without or with non-phospho peptide, detected Beta Catenin (Ser675) in 10 µg of SW480 cell lysate. A loss of signal was observed when a representative lot of this antibody was incubated with phopho peptide.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 200 µL
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