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品种反应性 主要应用 宿主 格式 抗体类型 M, R IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN492 描述 Anti-EPAC2 Antibody Alternate Names - Exchange factor directly activated by cAMP 2
- Rap guanine nuclear exchange factor 4
- RAPGEF4
- cAMPGEF-II
- CGEF2
背景信息 Exchange factor directly activated by cAMP 2 (EPAC2), also known as Rap guanine nuclear exchange factor 4 (RAPGEF4) and cAMP-regulated guanine nucleotide exchange factor II (cAMPGEF-II), belong to a family of cyclic adenosine monophosphate (cAMP) binding proteins that act as a guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B, and RAP2A small GTPases that are activated through cAMP binding. EPAC2 signaling plays a role in numerous cellular processes such as integrin-mediated cell adhesion, muscle contraction, learning and memory, cell proliferation, exocytosis and inflammation. EPAC2 has been found to induce synapse remodeling and depression, with mutations in its gene being found in patients with autism. EPAC2 is predominantly expressed in brain and adrenal gland. 产品信息 格式 Affinity Purified 控制 - Rat liver tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-EPAC2 Antibody is a highly specific rabbit polyclonal antibody, that targets Epac & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected EPAC2 in mouse liver tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human EPAC2. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseRat Species Reactivity Note Demonstrated to react with Rat and Mouse. Predicted to react with Human based on immunogen design. 抗体类型 Polyclonal Antibody 基因符号 - RAPGEF4
纯化方法 Antigen Affinity purified UniProt编号 - Q8WZA2
产品使用声明 质量保证 Evaluated by Western Blotting/Peptide Inhibition Assay in rat liver tissue lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected EPAC2 in 15 µg of rat liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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