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描述 概述 Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors that form a "prothrombinase" complex with Factor X, enabling its proteolytic activation of prothrombin to thrombin. 产品目录编号 219365 品牌系列 Calbiochem®
同义词 Proaccelerin, Labile Factor, Ac-globulin, Ac-g 参考 参考 Walker, F.J. 1992. J. Biol. Chem. 267, 19896.
Monkovic, D.D., and Tracy, P.B. 1990. J. Biol. Chem. 265, 17132.
Krishnaswamy, S., et al. 1989. J. Biol. Chem. 264, 3160.
Lee, C.D., and Mann, K.G. 1989. Blood 73, 185.
Krieg, U.C., et al. 1987. Biochemistry 26, 103.产品信息 CAS号 9001-24-5 形式 Liquid 配方 In 50% glycerol/H₂O (v/v). Molar Mass 300000 生物信息 纯度 ≥95% by SDS-PAGE 来源 Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 特异活性 ≥20 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-20°C). Do not store below -20°C.
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