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品种反应性 主要应用 宿主 格式 抗体类型 M, R IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN471 描述 Anti-TMEM18 Antibody Alternate Names - TMEM18
- Transmembrane protein 18
背景信息 Transmembrane protein 18 (TMEM18) is a transcription repressor and cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC). Recent studies have shown that overexpression of TMEM18 provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells, while functional inactivation of the gene resulted in an almost complete loss of migration activity. This evidence implies that TMEM18 could be a potential target in NSC-based glioma therapy. Other studies suggest that TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, and may play a CNS-related role in predisposition to obesity. 产品信息 格式 Affinity Purified 控制 - Rat brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-TMEM18 Antibody is a highly specific rabbit polyclonal antibody, that targets TMEM18 & has been tested in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected TMEM18 in mouse brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TMEM18 in mouse brain tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human TMEM18. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseRat Species Reactivity Note Demonstrated to react with Mouse and Rat. Predicted to react with Human based on immunogen design. 抗体类型 Polyclonal Antibody 基因符号 - TMEM18
纯化方法 Antigen Affinity purified UniProt编号 - Q96B42
产品使用声明 质量保证 Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected TMEM18 in 15 µg of rat brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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