merck millipore,默克密理愽
  • merck millipore,默克密理博,07-803,Anti-phospho-c-Kit (Tyr703) Antibody

  • merck millipore,默克密理博,07-803,Anti-phospho-c-Kit (Tyr703) Antibody

    产品名称：Anti-phospho-c-Kit (Tyr703) Antibody
    产品型号：07-803
    Anti-phospho-c-Kit (Tyr703) Antibody is an antibody against phospho-c-Kit (Tyr703) for use in WB.

    merck millipore,默克密理博,07-803,Anti-phospho-c-Kit (Tyr703) Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-803,Anti-phospho-c-Kit (Tyr703) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 07-803
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-phospho-c-Kit (Tyr703) Antibody
    Alternate Names
    • KIT, CD117, PBT, SCFR, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
    • KIT
    • CD117
    • PBT
    • SCFR
    产品信息
    格式 Affinity Purified
    演示 100 μL of affinity purified rabbit polyclonal IgG in 50% storage buffer (PBS (without Mg2+ and Ca2+), pH 7.3 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide).
    应用
    应用 Anti-phospho-c-Kit (Tyr703) Antibody is an antibody against phospho-c-Kit (Tyr703) for use in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Peptide corresponding to amino acid region encompassing the human phospho-c-Kit (Tyr703).
    宿主 Rabbit
    特异性 Recognizes phosphorylated c-Kit (Tyr703)
    同种型 IgG
    品种反应性 Human
    Species Reactivity Note Expected to react with mouse and rat based on sequence similarity, but have not been tested.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001093772.1
    • NM_000222.2
    Entrez基因汇总 This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
    基因符号
    • c-kit
    • KIT
    • C-Kit
    • PBT
    • CD117
    • SCFR
    修改
    • Phosphorylation
    纯化方法 Immunoaffinity purified
    UniProt编号
    • P10721
    UniProt汇总 FUNCTION: SwissProt: P10721 # This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K).
    SIZE: 976 amino acids; 109865 Da
    SUBUNIT: Interacts with APS. Interacts with the tenth PDZ domain of MPDZ.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    DISEASE: SwissProt: P10721 # Defects in KIT are a cause of piebaldism [MIM:172800]. Piebaldism is an autosomal dominant genetic developmental abnormality of pigmentation characterized by congenital patches of white skin and hair that lack melanocytes. & Defects in KIT are a cause of gastrointestinal stromal tumor (GIST) [MIM:606764]. & Defects in KIT have been associated with testicular tumors [MIM:273300]. It includes germ cell tumor (GCT) or testicular germ cell tumor (TGCT).
    SIMILARITY: SwissProt: P10721 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated by immunoblot.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -80°C.
    Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,07-803,Anti-phospho-c-Kit (Tyr703) Antibody

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