- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
- merck millipore,默克密理博,ABN46,Anti-DISC1 Antibody
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN46 描述 Anti-DISC1 Antibody Alternate Names - Disrupted in schizophrenia 1 protein
背景信息 Disrupted in schizophrenia 1 (DISC1) is a candidate gene for susceptibility to schizophrenia. It was discovered through chromosomal analysis of a large Scottish family whose members exhibited schizophrenia and related psychiatric disorders. Through yeast two-hybrid screening, it was discovered that DISC1 interacts with many members of the centrosome and cytoskeletal system including MAP1A and Nudel. More recently, DISC1 has been found to regulate the transport of a complex containing Nudel, the lissencephaly-1 (LIS1) protein, and 14-3-3epsilon from neuronal cell bodies to the axons by the action of the microtubule-dependent directed motor protein kinesin-1, also known as KIF5A. Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation. DISC1 has at least four known isoforms. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Disc1 using this rabbit polyclonal antibody, Anti-DISC1 Antibody validated for use in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human DISC1 near the N-terminus. 表位 Near N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 -
">NP_001012975.1
基因符号 - KIAA0457
- DISC1
纯化方法 Affinity purified UniProt编号 - Q9NRI5
产品使用声明 质量保证 Evaluated by Western Blotting in human hippocampus tissue lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected DISC1 in 10 µg of human hippocampus tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MAB88079,Anti-Heat Shock Factor II Antibody, clone 3E2
下一件merck millipore产品：merck millipore,默克密理博,70823,pTriEx™-3 DNA - Novagen
相关产品
merck millipore,默克密理博,MAB3480,Anti-CFTR Antibody, a.a. 1370-1380, clone M3A7
merck millipore,默克密理博,17-317,Protein Phosphatase Inhibitor Set
merck millipore,默克密理博,MAB1617,Anti-Kinesin Antibody, light chain, clone L2
merck millipore,默克密理博,233630,Cryptotanshinone - CAS 35825-57-1 - Calbiochem
merck millipore,默克密理博,MAB88079,Anti-Heat Shock Factor II Antibody, clone 3E2
merck millipore,默克密理博,70823,pTriEx™-3 DNA - Novagen
merck millipore,默克密理博,ST1682,Anti-COPS2 Mouse mAb (4B12)
merck millipore,默克密理博,PC373,Anti-p40 (5-17) Rabbit pAb
merck millipore,默克密理博,ABC373,Anti-HLA Antibody-DRB1
merck millipore,默克密理博,SF-493,FGF2; Human, Cyanine 5, RNA Detection Probe,SmartFlare