merck millipore,默克密理博,ABC373,Anti-HLA Antibody-DRB1

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merck millipore,默克密理博,ABC373,Anti-HLA Antibody-DRB1
产品名称：Anti-HLA Antibody-DRB1
产品型号：ABC373
Detect HLA using this rabbit polyclonal antibody, Anti-HLA Antibody-DRB1 validated for use in western blotting.

merck millipore,默克密理博,ABC373,Anti-HLA Antibody-DRB1

产品介绍

merck millipore,默克密理博,ABC373,Anti-HLA Antibody-DRB1

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABC373
描述	Anti-HLA Antibody-DRB1
Alternate Names	HLA-DRB1 HLA class II histocompatibility antigen, DRB1-1 beta chain MHC class II antigen DRB1*1 DR-1 DR1
背景信息	HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. HLA-DRB1 binds peptides derived from antigens that access the endocytic route of antigen presenting cells and presents them on the cell surface for recognition by the CD4 T-cells. Class II molecules are expressed in antigen presenting cells B lymphocytes, dendritic cells, macrophages. HLA-Drb1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. HLA-DRB1 has been shown to be a relevant marker of bone marrow derived mesenchymal stem cells and their osteogenic derivatives.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Detect HLA using this rabbit polyclonal antibody, Anti-HLA Antibody-DRB1 validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	GST-tagged fusion protein corresponding to human HLA-DRB1.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Human
抗体类型	Polyclonal Antibody
基因符号	HLA-DRB1
纯化方法	Antigen Affinity purified
UniProt编号	P04229

产品使用声明
质量保证	Evaluated by Western Blotting in A375 cell lysate. Western Blotting Analysis: A 1:300 dilution of this antibody detected HLA-DRB1 in A375 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.